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| Application Value of Pneumatic Therapy Combined with Enoxaparin Sodium in Preventing Lower Extremity Deep Vein Thrombosis after Cesarean Section |
| XU Xia, SONG Xiaoqing, LIU Shuzhi |
| Department of Obstetrics and Gynecology, Huaxian People's Hospital, Anyang Henan 456400 |
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Abstract 【Objective】 To explore the application value of pneumatic therapy combined with enoxaparin sodium in preventing lower extremity deep vein thrombosis (DVT) after cesarean section. 【Methods】 A total of 130 puerperae who underwent cesarean section in our hospital from May 2023 to May 2024 were enrolled and randomly divided into an observation group and a control group using a random number table, with 65 cases in each group. The control group received pneumatic therapy after cesarean section, while the observation group received pneumatic therapy combined with enoxaparin sodium after cesarean section. The incidence of lower extremity DVT, adverse reactions, hemorheological indexes, coagulation function indexes, inflammatory factor levels, and vascular endothelial function indexes of the two groups were compared after cesarean section. 【Results】 The incidence of lower extremity DVT in the observation group was 1.54% (1/65), which was significantly lower than 10.77% (7/65) in the control group, with a statistically significant difference (χ2=4.795, P=0.028). After treatment, the plasma viscosity, whole blood low-shear viscosity, and whole blood high-shear viscosity in the observation group were lower than those in the control group; the fibrinogen level was lower than that in the control group; the activated partial thromboplastin time, thrombin time, and prothrombin time were shorter than those in the control group, and all differences were statistically significant (P<0.05). After treatment, the levels of intercellular adhesion molecule 1, platelet-activating factor, matrix metalloproteinase 9, endothelin-1, and vascular endothelial growth factor in the observation group were lower than those in the control group (P<0.05). 【Conclusion】 Pneumatic therapy combined with enoxaparin sodium can prevent the occurrence of postoperative lower extremity DVT by improving the postoperative hypercoagulable state of puerperae after cesarean section, reducing the levels of inflammatory factors, and reducing vascular endothelial damage.
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Received: 14 May 2025
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