HGI、cys C水平与糖尿病视网膜病变程度的相关性

doi:10.3969/j.issn.1671-7171.2026.03.016

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Abstract 【Objective】 To explore the correlation of glycated hemoglobin variability index (HGI) and cystatin C (cys C) levels with the severity of diabetic retinopathy. 【Methods】 A total of 170 patients with diabetic retinopathy treated in our hospital from June 2023 to October 2024 were selected and divided into the non-proliferative retinopathy group (n=98) and the proliferative retinopathy group (n=72) based on the severity of diabetic retinopathy. Additionally, 83 patients with simple diabetes were selected as the control group (simple diabetes group). The correlations between HGI, cys C levels and the severity of diabetic retinopathy were analyzed. 【Results】 The proportion of high HGI and cys C levels in the proliferative retinopathy group were higher than those in the non-proliferative retinopathy group and the simple diabetes group (P<0.05). Both HGI and cys C levels were positively correlated with the severity of diabetic retinopathy (P<0.05). The duration of diabetes, fasting blood glucose (FPG), glycated hemoglobin (HbA1c), proportion of high HGI and cys C levels in the proliferative retinopathy group were higher than those in the non-proliferative retinopathy group (P<0.05). The duration of diabetes, HbA1c, high HGI and cys C were independent risk factors for proliferative diabetic retinopathy (P<0.05). The sensitivity, specificity and AUC of the combined HGI and cys C levels in predicting proliferative diabetic retinopathy were 80.56%, 97.96% and 0.893, respectively. 【Conclusion】 Both HGI and cys C levels are closely related to diabetic retinopathy. The clinical detection of HGI and cys C levels can be used as sensitive indicators for predicting proliferative diabetic retinopathy.

Key words： Diabetic Retinopathy Chalones Correlation of Data

Received: 26 December 2025

PACS:

R587.1

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	WANG Feiyan
	HU Xumeng
	LI Le

Cite this article:

WANG Feiyan,HU Xumeng,LI Le. Correlation of HGI and cys C Levels with Diabetes Retinopathy[J]. JOURNAL OF CLINICAL RESEARCH, 2026, 43(3): 411-414.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2026.03.016 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2026/V43/I3/411

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