Ⅰ期心脏康复对STEMI患者急诊PCI术后心功能及血清STIM1水平的影响

doi:10.3969/j.issn.1671-7171.2025.12.009

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Abstract 【Objective】 To investigate the effect of Phase Ⅰ cardiac rehabilitation on cardiac function and serum stromal interaction molecule 1 (STIM1) level in patients with ST-segment elevation myocardial infarction (STEMI) after emergency percutaneous coronary intervention (PCI). 【Methods】 A total of 100 STEMI patients who underwent emergency PCI in the Changhai Hospital and the Kongjiang Hospital from January to December 2024 were selected and randomly divided into a control group and a rehabilitation group, with 50 cases in each group. The control group received routine treatment after emergency PCI, while the rehabilitation group received Phase Ⅰ cardiac rehabilitation on the basis of routine treatment. Left ventricular ejection fraction (LVEF), N-terminal pro-brain natriuretic peptide (NT-proBNP) level, STIM1 level, physical component summary (PCS) score, mental component summary (MCS) score, peak oxygen uptake (VO₂/kg), metabolic equivalent (MET), oxygen pulse (VO₂/HR), ventilation-to-carbon dioxide production ratio (VE/VCO₂ slope) and the occurrence of major adverse cardiovascular events (MACE) were compared between the two groups before treatment and 1 month after treatment. 【Results】 One month after treatment, the LVEF, PCS score and MCS score in the rehabilitation group were significantly higher than those in the control group (P<0.05), while the serum levels of NT-proBNP and STIM1 were significantly lower than those in the control group (P<0.05). The peak VO₂/kg, MET and VO₂/HR in the rehabilitation group were higher than those in the control group (P<0.05), and the VE/VCO₂ slope was lower than that in the control group (P<0.05). There was no significant difference in the incidence of MACE between the two groups (P>0.05). 【Conclusion】 Phase Ⅰcardiac rehabilitation has a significant improvement effect on STEMI patients after emergency PCI. It can not only effectively improve cardiac function, reduce the risk of heart failure, but also enhance the quality of life and alleviate psychological burden of the patients. It may also promote patient recovery by reducing serum STIM1 level, which has good clinical promotion value.

Key words： Cardiac Rehabilitation ST Elevation Myocardial Infarction Acute Disease Percutaneous Coronary Intervention Heart Function Tests

Received: 19 February 2025

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R542.22

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.12.009 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I12/2046

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