床旁纤维支气管镜灌洗术在急性酒精中毒合并吸入性肺炎患者中的应用效果

doi:10.3969/j.issn.1671-7171.2025.08.015

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Abstract 【Objective】To explore the application effect of bedside flexible bronchoscope lavage in patients with acute ethanol intoxication complicated by aspiration pneumonia. 【Methods】A total of 108 patients with acute ethanol intoxication complicated by aspiration pneumonia admitted to our hospital from December 2020 to December 2023 were selected. According to the order of admission, they were divided into a control group and an observation group, with 54 cases in each group. The control group received conventional drug treatment, while the observation group was given additional bedside flexible bronchoscope lavage on the basis of the control group. The serum inflammatory factor levels and oxygen metabolism indicators of the two groups before and after treatment were compared. 【Results】After treatment, the levels of serum high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) in the observation group were lower than those in the control group (P<0.05). After treatment, in both groups, oxygen delivery (DO₂), oxygenation index (PaO₂/FiO₂), and arterial oxygen content (CaO₂) increased, while oxygen consumption (VO₂) and lactate (Lca) decreased; and the observation group was better than the control group (P<0.05). 【Conclusion】The application of bedside flexible bronchoscope lavage in patients with acute ethanol intoxication complicated by aspiration pneumonia can effectively reduce the inflammatory response and improve the patients' oxygen metabolism indicators.

Key words： Alcoholic Intoxication Pneumonia, Aspiration Bronchoscopy Bronchoalveolar Lavage

Received: 16 October 2024

PACS:

R595.6

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	LIU Yuan
	MA Ning

Cite this article:

LIU Yuan,MA Ning. Application Effect of bedside Flexible Bronchoscope Lavage in Patients with Acute Ethanol Intoxication Complicated by Aspiration Pneumonia[J]. JOURNAL OF CLINICAL RESEARCH, 2025, 42(8): 1347-1349.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.08.015 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I8/1347

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