床旁纤维支气管镜灌洗术在急性酒精中毒合并吸入性肺炎患者中的应用效果

doi:10.3969/j.issn.1671-7171.2025.08.015

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Abstract 【Objective】To explore the application effect of bedside flexible bronchoscope lavage in patients with acute ethanol intoxication complicated by aspiration pneumonia. 【Methods】A total of 108 patients with acute ethanol intoxication complicated by aspiration pneumonia admitted to our hospital from December 2020 to December 2023 were selected. According to the order of admission, they were divided into a control group and an observation group, with 54 cases in each group. The control group received conventional drug treatment, while the observation group was given additional bedside flexible bronchoscope lavage on the basis of the control group. The serum inflammatory factor levels and oxygen metabolism indicators of the two groups before and after treatment were compared. 【Results】After treatment, the levels of serum high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) in the observation group were lower than those in the control group (P<0.05). After treatment, in both groups, oxygen delivery (DO₂), oxygenation index (PaO₂/FiO₂), and arterial oxygen content (CaO₂) increased, while oxygen consumption (VO₂) and lactate (Lca) decreased; and the observation group was better than the control group (P<0.05). 【Conclusion】The application of bedside flexible bronchoscope lavage in patients with acute ethanol intoxication complicated by aspiration pneumonia can effectively reduce the inflammatory response and improve the patients' oxygen metabolism indicators.

Key words： Alcoholic Intoxication Pneumonia, Aspiration Bronchoscopy Bronchoalveolar Lavage

Received: 16 October 2024

PACS:

R595.6

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	LIU Yuan
	MA Ning

Cite this article:

LIU Yuan,MA Ning. Application Effect of bedside Flexible Bronchoscope Lavage in Patients with Acute Ethanol Intoxication Complicated by Aspiration Pneumonia[J]. JOURNAL OF CLINICAL RESEARCH, 2025, 42(8): 1347-1349.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.08.015 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I8/1347

[1] 龚志均. 床边纤维支气管镜灌洗术联合灌注清开灵注射液治疗急性乙醇中毒合并吸入性肺炎研究[J].现代中西医结合杂志, 2018,27(21):86-89.
[2] 付黎明, 朱平, 李春燕. 纤维支气管镜吸痰灌洗联合机械排痰治疗吸入性肺炎并发呼吸衰竭疗效观察[J].新乡医学院学报, 2018,215(7):67-70.
[3] 张亚乐,张维华. 支气管肺泡灌洗术治疗重症肺炎患儿的临床疗效[J].医学临床研究,2025,42(1):5-7.
[4] 汪建英, 方强, 马建忠, 等. 纤维支气管镜肺泡灌洗吸痰术联合血必净治疗危重症监护室肺部感染患者的效果及对BNP、TLR-4水平的影响[J].中国全科医学, 2018, 21(S2):73-75.
[5] 陈海玉, 曾广志, 唐召力,等. 纤维支气管镜肺泡灌洗术治疗重症肺炎对患者全身炎症反应、呼吸力学指标的影响[J].中国医师杂志, 2019, 21(8):1251-1253.
[6] 吴磊, 王思. 纤维支气管镜肺泡灌洗联合抗生素治疗慢性阻塞性肺疾病合并呼吸衰竭的疗效分析[J].中国临床医生杂志, 2018, 46(5):530-532.
[7] 李春辉, 罗刚, 陈涛, 等. 痰热清注射液经纤维支气管镜肺灌洗术对重型颅脑外伤并肺部感染患者的临床疗效及炎性因子的影响[J].中国医师杂志, 2018,1(4):592-594.
[8] 杨慧. 阿米卡星联合纤维支气管镜肺泡灌洗术治疗支气管扩张合并铜绿假单胞菌感染临床研究[J].陕西医学杂志, 2020, 49(1):99-101.
[9] 杨盛泉, 张元铭, 王贵强. 胸腺肽α1注射液联合床边纤维支气管镜支气管肺泡灌洗术对老年重症肺炎患者外周血CD4⁺/CD8⁺水平及预后的影响[J].临床和实验医学杂志, 2019, 18(4):406-409.
[10] 李刚, 张素巧, 张国强,等. 纤维支气管镜下生理盐水灌洗在重症吸入性肺炎患者中的应用[J].临床药物治疗杂志, 2019, 17(3):21-24.
[11] 蒋南红,王德运,席毛毛,等. 纤维支气管镜气道灌洗治疗特重度烧伤合并重度吸入性损伤患者的回顾性研究[J].中华烧伤杂志, 2020, 36(4):252-259.
[12] 沈妍,李欣,秦晓娟. 纤维支气管镜肺灌洗对AECOPD合并Ⅱ型呼吸衰竭患者肺功能及炎性因子的影响[J].疑难病杂志, 2018,17(7):37-41.
[13] 李材忠.肺泡灌洗术联合氨溴索局部用药治疗支气管扩张合并感染的疗效及对IL-2和IL-4的影响[J].广西医科大学学报, 2019, 36(2):69-72.