3D Bravo联合Cube Flair增强序列在微小脑转移瘤诊断中的临床应用价值<sup>*</sup>

doi:10.3969/j.issn.1671-7171.2025.08.004

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (1703 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract 【Objective】To explore the clinical application value of 3D Bravo combined with Cube Flair enhanced sequence in the diagnosis of small cerebral metastatic tumors. 【Methods】Seventy-five tumor patients with cerebral metastases admitted to our hospital from January 2022 to March 2024 were selected. Cranial enhanced FSE T₁WI, 3D Bravo, and Cube Flair scans were performed on a 1.5T magnetic resonance imaging scanner. The number of small cerebral metastatic tumor lesions detected by the three enhanced sequences and the 3D Bravo combined with Cube Flair sequence were counted respectively, and the diagnostic results were confirmed through two or more consecutive follow-up reviews. 【Results】A total of 420 small cerebral metastatic tumor lesions were found in 75 patients. Among them, 279 metastatic tumor lesions were found by conventional FSE T₁WI enhancement, with a detection rate of 66.4%; 339 metastatic tumor lesions were found by the 3D Bravo enhanced sequence, with a detection rate of 80.7%; 377 metastatic tumor lesions were found by the Cube Flair enhanced sequence, with a detection rate of 89.8%; and 402 metastatic tumor lesions were found by the 3D Bravo combined with Cube Flair enhanced sequence, with a detection rate of 95.7%. There were statistically significant differences in the detection rates of small cerebral metastatic tumor lesions among the FSE T₁WI, 3D Bravo, Cube Flair enhanced sequences and the 3D Bravo combined with Cube Flair enhanced sequence (P<0.05). The Cube Flair sequence had false-positive cases in the follow-up diagnosis of cystic cerebral metastatic tumors. 【Conclusion】The 3D Bravo combined with Cube Flair enhanced sequence can significantly improve the detection rate of small cerebral metastatic tumor lesions, especially in the diagnosis of small metastatic tumors in the superficial area of the brain, which has significant clinical application value and can be an alternative sequence to the conventional FSE T₁WI enhanced sequence.

Key words： Neoplasm Metastasis Brain Neoplasms Magnetic Resonance Imaging Diagnosis

Received: 16 January 2025

PACS:

R739.41

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2025.08.004 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2025/V42/I8/1307

[1] LAMBA N, WEN P Y, AIZER A A. Epidemiology of brain metastases and leptomeningeal disease[J].Neuro Oncol,2021,23(9): 1447-1456.
[2] NIRANJAN A, MONACO E, FLICKINGER J, et al. Guidelines for multiple brain metastases radiosurgery[J].Prog Neurol Surg,2019,34: 100-109.
[3] VOGELBAUM M A, BROWN P D, MESSERSMITH H, et al. Treatment for brain metastases: ASCO-SNO-ASTRO Guideline[J].J Clin Oncol,2022,40(5): 492-516.
[4] 余留森,马小静.CUBET₂FLAIR序列在脑内微小转移瘤诊断中的应用[J].中国中西医结合影像学杂志,2015,13(5):491-493.
[5] TADROS S, RAY-CHAUDHURY A. Pathological Features of Brain Metastases[J].Neurosurg Clin N Am,2020, 31(4): 549-564.
[6] 吕秀花, 赵海峰, 董军强, 等.磁共振3DBravo增强扫描序列在脑转移瘤的临床应用价值[J].医学影像学杂志, 2023, 33(12):2164-2166.
[7] 龚建中, 乔建兰, 郝艳. 增强T₂ FLAIR与增强T₁WI在颅内肿瘤性病变中的对照研究[J].中国医学计算机成像杂志,2019,25(6): 503-508.
[8] 颜兵, 王玉群, 周爱平, 等. 增强T₂FLAIR序列在神经系统病变中的应用价值[J].影像研究与医学应用, 2019,3(22): 218-219.
[9] 郑广平, 王立非, 云永兴, 等. T₂ FLAIR增强和T₁WI-3D-TFE增强序列对结核性脑膜炎诊断的对比研究[J].磁共振成像,2019,10(12):895-898.
[10] KURODA R, NAKAGAWA H, UCHIDA Y, et al. Immune-related aseptic meningitis diagnosed by Cube FLAIR on enhanced magnetic resonance imaging for a lung cancer patient administered atezolizumab:a case report[J].Respirol Case Rep,2023,11(2): e01076.
[11] 龚逢杰,杨立,田娟,等.磁共振3D Bravo序列在肺癌脑转移瘤诊断中的临床价值[J].医学临床研究,2016,33(11):2193-2195.
[12] 王丽,韦敏,贺雪平,等.肺癌靶向治疗后脑膜转移的3D FLAIR增强扫描研究[J].临床放射学杂志,2024,43(3):326-331.
[13] 包雪平, 曹亮, 葛涌钱. 磁共振Bravo序列与Cube Flair序列对肺癌脑转移患者的应用比较[J].中国CT和MRI杂志, 2015,13(2):1-3.
[14] 李丽红, 朱华勇, 李欣, 等. 磁共振增强CUBET₁WI序列检出肺癌脑转移微小病灶效能的研究[J].浙江医学,2021, 43(19): 2104-2108.
[15] 杨侃荣, 林焕杰, 李树强, 等. CUBE T₂FLAIR与3D BRAVO序列在脑转移瘤中的应用[J].现代医用影像学,2021,30(8): 1395-1398.

[1]	. [J]. JOURNAL OF CLINICAL RESEARCH, 2025, 42(8): 1408-1410.