夫妻双方年龄对夫精人工授精妊娠结局的影响<sup>*</sup>

doi:10.3969/j.issn.1671-7171.2024.09.002

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Abstract 【Objective】To explore the effect of age on the pregnancy outcome of artificial insemination by husband(AIH). 【Methods】A retrospective analysis was conducted on 110 couples who underwent AIH at the Reproductive Medicine Center of Hunan People's Hospital from November 2017 to November 2023. The total number of cycles of artificial insemination with husband's sperm was 202. The clinical pregnancy rate and spontaneous abortion rate of AIH in different age groups of the couples were compared, and the proportion of AIH cycles ≥ 3 in different age groups of the female partner and the abnormal sperm quality rate in different age groups of the male partner were compared. 【Results】There was no statistically significant difference (P>0.05) in the duration of infertility, endometrial thickness on trigger day, and serum estradiol (E₂) and progesterone (P) levels between patients aged ≥ 35 and those aged<35. The serum E₂ level on trigger day in patients with clinical pregnancy age ≥ 35 years old was lower than that in patients with age<35 years old, and the difference was statistically significant (P<0.05); The spontaneous abortion rate during the clinical pregnancy cycle in the age group ≥ 35 years old is higher than that in the age group<35 years old, and the difference is statistically significant (P<0.05). The proportion of AIH cycles ≥ 3 times in the female age group ≥ 35 years old was significantly higher than that in the age group<35 years old, and the difference was statistically significant (P<0.05). The abnormal rate of sperm quality in the male age group ≥ 35 years old is higher than that in the age group<35 years old, and the difference is statistically significant (P<0.05). 【Conclusion】The age of the female partner has a certain impact on the incidence of spontaneous abortion after AIH clinical pregnancy. For infertile patients aged 35 years or older, more active assisted reproductive methods can be considered. The age of the male partner is an important factor affecting sperm quality.

Key words： Insemination, Artificial, Homologous Pregnancy Outcome Age Distribution

Received: 15 May 2024

PACS:

R711.6

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	ZENG Qianling
	ZHU Hailun

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ZENG Qianling,ZHU Hailun. The Influence of Marital Age on the Pregnancy Outcome of Artificial Insemination with Husband's Sperm[J]. JOURNAL OF CLINICAL RESEARCH, 2024, 41(9): 1285-1288.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2024.09.002 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2024/V41/I9/1285

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