|
|
|
| Clinical Effect of Electromagnetic Navigation Assisted Neuroendoscopic Hematoma Clearance Surgery in the Treatment of Hypertensive Intracerebral Hemorrhage |
| DU Juan, LIU Tingting, CHEN Sujie |
| The Second Affiliated Hospital of Zhengzhou University,Zhengzhou Henan 450000 |
|
|
|
|
Abstract 【Objective】To investigate the efficacy of electromagnetic navigation assisted neuroendoscopic hematoma evacuation in the treatment of hypertensive intracerebral hemorrhage (HICH) patients and its impact on short-term prognosis. 【Methods】 A retrospective analysis was conducted on the clinical data of 102 HICH patients admitted to our hospital. According to different surgical plans, they were divided into the observation group (treated with electromagnetic navigation assisted neuroendoscopic hematoma evacuation) and the control group (treated with conventional neuroendoscopic hematoma evacuation), with 51 cases in each group. Two groups of perioperative indicators, National Institutes of Health Stroke Scale (NIHSS) scores before and after surgery, Modified Rankin Scale (mRS) scores, oxidative stress indicators (SOD, GSH-Px, MDA), vascular endothelial function indicators (AVP, Ang-1, ET), and incidence of complications were compared. 【Results】The residual hematoma volume and hematoma clearance rate in the observation group were lower than those in the control group after surgery, and the hospitalization time was shorter than that in the control group, with statistical significance (P<0.05). At 1 and 3 months after surgery, the NIHSS and mRS scores in both groups were lower than before surgery, and the observation group was lower than the control group, with statistical significance (P<0.05). One month after surgery, the levels of SOD and GSH-Px in the serum of both groups were higher than before surgery, and the level of MDA in the serum was lower than before surgery. The differences in these indicators between the two groups were statistically significant (P<0.05). One month after surgery, the levels of serum AVP, Ang-1, and ET in both groups were lower than before surgery, and the observation group was lower than the control group, with statistical significance (P<0.05). The incidence of complications in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). 【Conclusion】Electromagnetic navigation assisted neuroendoscopic hematoma removal surgery can improve neurological function and prognosis in HICH patients, optimize perioperative indicators, alleviate oxidative stress, improve vascular endothelial function, and reduce the risk of complications.
|
|
Received: 08 July 2023
|
|
|
|
|
|
[1] 张姗姗,甄志勇.超早期小骨窗微创术对高血压脑出血的疗效及对血清VEGF、Ang-1水平和神经功能指标的影响分析[J].解放军医药杂志,2021,33(6):54-58.
[2] 赵鑫,龚琳.软通道微创穿刺引流术联合七叶皂苷钠治疗高血压脑出血的临床效果[J].中西医结合心脑血管病杂志,2021,19(10):1742-1744.
[3] 王喜旺,王晓燕,张宁,等.高血压性脑出血的神经内镜手术治疗体会[J].中国临床神经外科杂志,2022,27(8):692-693.
[4] 胡志卿,范学政,李明,等.神经内镜辅助3D-slicer导航在高血压脑出血手术中的应用及预后分析[J].神经损伤与功能重建,2021,16(12):756-758.
[5] 黄毅,黄常坚,黄建荣.3D Slicer软件联合手机导航辅助神经内镜手术治疗基底节区高血压脑出血患者的临床效果[J].广西医学,2022,44(12):1425-1428.
[6] 郭振宇,黄廷钦,周任,等.电磁导航技术在神经内镜下血肿清除术中的应用[J].中华神经医学杂志,2020,19(5):477-482.
[7] 陈立珂,蓝美锐,陈岷辉.开颅血肿清除和神经导航引导下血肿抽吸术治疗高血压脑出血的疗效观察[J].实用医院临床杂志,2020,17(4):185-187.
[8] 艾昕,苏杰,姚美,等.高血压脑出血病人神经内镜血肿清除术后预后不良发生率及相关因素分析[J].蚌埠医学院学报,2023,48(3):402-405.
[9] 宋飞,张毅,廖卜生,等.神经内镜术与传统开颅术治疗高血压脑出血疗效比较的meta分析[J].重庆医学,2021,50(20):3531-3535.
[10] 匡德利,许西海,符艳松.神经内镜辅助去骨瓣血肿清除术治疗高血压脑出血的效果及对患者神经功能、预后的影响[J].临床误诊误治,2021,34(5):106-111.
[11] 肖欢,朱莲,冯晓荣.胞磷胆碱联合奥拉西坦治疗高血压脑出血临床效果及对炎性因子、氧化应激、NIHSS评分的影响[J].解放军医药杂志,2021,33(12):88-91.
[12] 李强,陈刚,柳再明.软通道微创治疗高血压脑出血对患者血清氧化应激指标、神经功能康复的影响[J].医学临床研究,2020,37(1):149-151.
[13] 李德辉,郭东亮.微创颅内血肿清除术联合亚低温治疗高血压脑出血的效果及对血管活性因子、日常生活活动能力的影响[J].临床误诊误治,2022,35(9):97-101.
[14] 邵政,柳泽彬,肖铮铮,等.不同手术时机小骨窗微创血肿清除术对高血压脑出血患者炎症因子、预后及血清Ang-1、ET、AVP水平的影响[J].现代生物医学进展,2021,21(20):3979-3983. |
|
|
|
2024, Vol. 41 
