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| Clinical Efficacy of Qingao Xiaojitang in Treating Pediatric Digestive Disorders and its Impact on Gastrointestinal Function Indicators |
| ZHAO Caihong, CONG Minghui, FANG Kun, et al |
| Qingdao Maternal and Child Health and Family Planning Service Center, Qingdao Shandong 266000 |
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Abstract 【Objective】To explore the clinical efficacy of Qingao Xiaojitang in treating pediatric digestive disorders and its impact on gastrointestinal function indicators. 【Methods】A total of 124 children with digestive disorders admitted to two hospitals from January 2021 to March 2022 were selected and randomly divided into an observation group (treated with domperidone combined with Qingao Xiaojitang) and a control group (treated with domperidone) using a random number table method, with 62 cases in each group. Two groups were compared in terms of clinical efficacy, TCM syndrome scores, gastrointestinal hormone levels, and changes in gastric motility before and after treatment.【Results】The total effective rate of the observation group was 90.32% (56/62), which was higher than the control group's 75.81% (47/62), and the difference was statistically significant (χ2=4.644, P<0.05). After treatment, the scores of early satiety, nausea, abdominal distension, belching, etc. in both groups were lower than before treatment, and the observation group was lower than the control group, with a statistically significant difference (P<0.05). After treatment, the levels of MTL, GAS, and GHR in both groups of children were higher than before treatment, and the observation group was higher than the control group, with statistical significance (P<0.05). After treatment, the frequency and amplitude of gastric contraction waves in both groups were significantly higher than before treatment, and the observation group was higher than the control group, with a statistically significant difference (P<0.05).【Conclusion】 Qingao Xiaojitang has significant clinical efficacy in treating pediatric digestive disorders, effectively alleviating gastrointestinal hormone levels and improving gastric motility indicators.
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Received: 06 December 2023
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[1] 张蕾,吕健,谢雁鸣. 肠炎宁颗粒治疗小儿消化不良有效性和安全性的系统评价与Meta分析[J].中国全科医学,2022,25(14):1765-1771.
[2] SAYUK G S, GYAWALI C P. Functional dyspepsia: diagnostic and therapeutic approaches[J].Drugs,2020,80(13):1319-1336.
[3] 吴晓燕,秦侃,王杨,等. 酪酸梭菌活菌散联合多潘立酮治疗小儿功能性消化不良的疗效及相关作用机制[J].中国现代医学杂志,2021,31(14):35-39.
[4] 刘瑞华,刘绍能. 中医治疗功能性消化不良撷要[J].江苏中医药,2021,53(5):47-50.
[5] SONG J, YANG L, SU S, et al. Agreement of gastroenterologists in traditional Chinese medical differential diagnosis of functional dyspepsia compared with traditional Chinese medical practitioners: A prospective, multicenter study[J].J Dig Dis,2020,21(7):399-405.
[6] 童晶晶,潘琦,高晓阳,等. 罗马Ⅲ标准在功能性消化不良诊断和鉴别诊断中的价值[J].中华消化杂志,2009,29(1):25-28.
[7] 张伯礼,吴勉华.中医内科学[M].10版.北京:中国中医药出版社,2016:25-28.
[8] SUN R, ZHOU J, QU Y Z, et al. Resting-state functional brain alterations in functional dyspepsia: Protocol for a systematic review and voxel-based meta-analysis[J].Medicine (Baltimore),2020,99(48):232-242.
[9] HA N Y, LEE H N, JEONG H I, et al. Safety and efficacy of Soyo-san for the treatment of functional dyspepsia: A protocol for systematic review and meta-analysis[J].Medicine (Baltimore), 2020,99(39):223-229.
[10] KO S J, CHO S H, KIM K J, et al. Herbal medicine Banha-sasim-tang for the treatment of functional dyspepsia protocol for a systematic review of randomized controlled trials[J].Medicine (Baltimore),2019,98(22):157-160.
[11] 石敬依,周滔,蔡文君,等. 基于中医证型的功能性消化不良动物模型的研究进展[J].现代中西医结合杂志,2021,30(17):1923-1928.
[12] WANG Y P, LIU B, FU X Q, et al. Efficacy and safety of Si-Jun-Zi-Tang-based therapies for functional (non-ulcer) dyspepsia: a meta-analysis of randomized controlled trials[J].BMC Complement Med Ther,2021,21(1):11.
[13] 张馨蕊. 芩膏消积汤治疗小儿积滞(乳食内积证)的临床研究[D]. 长春:长春中医药大学,2020.
[14] 王智. 理气安胃汤治疗功能性消化不良的疗效观察及其对胃肠激素和胃动力的影响[J].中国中医药科技,2020,27(2):179. |
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2024, Vol. 41 
