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| Clinical Effect of Yinchenhao Decoction on Postoperative Diabetes Foot |
| PENG Linfeng, WANG Yuzhen, ZHAO Zhiguo, et al |
| Department of Vasculature, Shanghai Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai 200082 |
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Abstract 【Objective】To investigate the clinical efficacy of Yinchenhao Decoction in the treatment of diabetes foot after operation.【Methods】The clinical data of 95 patients with diabetes foot who underwent surgical treatment in our hospital from January to December 2023 were retrospectively analyzed. According to the different treatment methods, they were divided into the control group (n=47, conventional treatment) and the observation group (n=48, conventional treatment + Yinchenhao Decoction modified treatment). We compared the clinical efficacy, postoperative recovery (bed rest time, bed rest time, anal exhaust time, hospital stay), wound improvement (wound area and depth, granulation tissue growth degree, wound healing time), and incidence of adverse reactions between two groups,and the symptom scores and serum inflammatory factors[ C-reactive protein(CRP), tumor necrosis factor-α(TNF-α), interleukin-4(IL-4), interleukin-5(IL-5)],blood glucose [fasting blood glucose(FPG), glycated hemoglobin (HbA1c)] and the levels of hemorheological indicators[erythrocyte sedimentation rate (ESR), fibrinogen (Fib), and plasma viscosity (PV) ]before and after treatment were statistically analyzed for both groups.【Results】The total effective rate of the observation group was 93.75%, significantly higher than the control group's 78.72% (P<0.05). Compared with the control group, the observation group had a shorter postoperative recovery time (P<0.05). After treatment, the wound area and depth of both groups decreased, and the observation group showed a more significant decrease (P<0.05); The growth degree of granulation tissue in the observation group was greater than that in the control group, and the wound healing time was shorter than that in the control group (P<0.05). After treatment, the levels of the symptom scores FPG, HbA1c, CRP, TNF-α, ESR, Fib, and PV for both groups were all reduced, and the observation group was lower than the control group (P<0.05); The levels of IL-4 and IL-5 both increased, and the observation group was higher than the control group (P<0.05). Both groups of patients showed no significant adverse reactions.【Conclusion】Yinchenhao Decoction can promote postoperative recovery and wound repair of diabetes foot, control blood sugar level, relieve symptoms, alleviate inflammatory reaction, improve hemorheology, improve efficacy, and will not increase the incidence of adverse reactions.
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Received: 29 February 2024
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2024, Vol. 41 
