Pipeline栓塞装置与支架辅助弹簧圈栓塞治疗大型脑动脉瘤的临床疗效比较

doi:10.3969/j.issn.1671-7171.2024.04.032

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Abstract 【Objective】To explore the clinical efficacy of Pipeline embolization device (PED) and stent assisted coil placement (SAC) in the treatment of large cerebral aneurysms. 【Methods】A retrospective analysis was conducted on the clinical data of 82 patients with intracranial aneurysms with a diameter of ≥ 10 mm admitted to our hospital from December 2017 to December 2021. Among them, 43 patients received PED treatment (PED group) and 39 patients received SAC treatment (SAC group). We compared the surgical results of two groups of patients, and compared the results of immediate digital subtraction angiography (DSA) and modified Rankin Scale (mRS) scores at admission and discharge between the two groups. Two groups of patients were followed up 12 months after surgery, and the mortality, recurrence, DSA examination results, and mRS score distribution were compared between the two groups at 6 and 12 months after discharge. 【Results】In this study, 82 patients successfully completed surgery, including 45 PEDs implanted in the PED group, 16 pure PEDs implanted, 25 PEDs combined with spring coil filling, and 2 double PEDs implanted. There was no statistically significant difference in the dense embolism rate between the two groups of immediate postoperative DSA examination results(P>0.05). There was no statistically significant difference in the distribution of mRS scores between the two groups at admission and discharge (P>0.05). There was no statistically significant difference in the incidence and mortality of perioperative complications between the two groups (P>0.05). At the 6-12 month follow-up after discharge, the dense embolism rate in the PED group was higher than that in the SAC group, and the differences were statistically significant (all P<0.05). The proportion of mRS scores ≤ 2 in the PED group for follow-up at 6 and 12 months after discharge was higher than that in the SAC group, and the differences were statistically significant (all P<0.05). 【Conclusion】The clinical efficacy and short-term prognosis of PED treatment for large intracranial aneurysms are comparable to those of SAC, but PED shows certain advantages in improving long-term prognosis.

Key words： Intracranial Aneurysm/SU Embolization, Therapeutic Treatment Outcome

Received: 20 January 2023

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R651.122

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	JIANG Ling
	YAO Huijuan
	WANG Chaochao
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Cite this article:

JIANG Ling,YAO Huijuan,WANG Chaochao, et al. Comparison of Clinical Efficacy between Pipeline Embolization Device and Stent Assisted Coil Embolization in the Treatment of Large Cerebral Aneurysms[J]. JOURNAL OF CLINICAL RESEARCH, 2024, 41(4): 594-597.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2024.04.032 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2024/V41/I4/594

[1] 宋志强, 朱安林, 陈锐锋,等. 颅内动脉瘤急症介入术后神经系统并发症相关因素探讨[J].介入放射学杂志,2019, 28(5):411-414.
[2] CHALOUHI N, JABBOUR P M, TJOUMAKARIS S I, et al. Treatment of large and giant intracranial aneurysms: cost comparison of flow diversion and traditional embolization strategies[J]. World Neurosurg,2013, 82(5):696-701.
[3] YANG P F, ZHAO K J, ZHOU Y, et al. Stent-assisted coil placement for the treatment of 211 acutely ruptured wide-necked intracranial aneurysms: a single-center 11-year experience[J].Radiology,2015, 276(2):545-552.
[4] LOPES D K, DONG-KYU J, SARUHAN C, et al. Morbidity and mortality in patients with posterior circulation aneurysms treated with the pipeline embolization device: a subgroup analysis of the international retrospective study of the pipeline embolization device[J].Neurosurgery,2018, 83(3):488-500.
[5] 郝以姝, 张志珺. 未破裂颅内动脉瘤破裂危险因素的研究进展[J].中华神经医学杂志, 2017, 16(1):95-99.
[6] 郭吉卫. 血管内介入与传统开颅手术治疗颅内动脉瘤的临床比较[J].神经损伤与功能重建, 2015, 10(4):350-351.
[7] BRINJIKJI W, KALLMES D, CLOFT H, et al. Age-related outcomes following intracranial aneurysm treatment with the Pipeline Embolization Device: a subgroup analysis of the intre PED registry[J].J Neurosurg,2016, 124(6):1726-1730.
[8] 程美雄, 张天, 谭海斌, 等. Pipeline血流导向装置治疗颈内动脉大型和巨大型动脉瘤的疗效分析[J].中华神经外科杂志, 2018, 34(5):447-450.
[9] 陈圣攀, 叶明, 张鹏. Pipeline血流导向装置治疗颅内动脉瘤的现状[J].中华神经外科杂志, 2016, 32(5):534-537.
[10] WANG B, GAO B L, XU G P, et al. Endovascular embolization is applicable for large and giant intracranial aneurysms: experience in one center with long-term angiographic follow-up[J].Acta Radiol,2015, 56(1):105-113.
[11] 丁伟, 黄乔春, 闵强, 等. Pipeline血流导向装置在治疗颈内动脉大型或巨大型宽颈动脉瘤中的初步应用[J].重庆医科大学学报, 2019, 44(6):797-801.
[12] 柯勋昌, 何旭英, 李西锋, 等. 血流导向装置Pipeline治疗颅内动脉瘤的近期疗效[J].中华神经医学杂志, 2017, 16(2):156-160.
[13] 贺迎坤, 李航, 白卫星, 等. Pipeline血流导向装置治疗颅内大动脉瘤的疗效分析[J].中华医学杂志, 2018, 98(27):2180-2183.