心脏超声相关参数、实验室指标对STEMI患者PCI治疗后短期预后的预测价值

doi:10.3969/j.issn.1671-7171.2024.04.010

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Abstract 【Objective】To investigate the value of cardiac ultrasound parameters and laboratory indexes in predicting short-term prognosis of patients with acute ST-segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI). 【Methods】A total of 80 STEMI patients admitted to Xi'an Gaoxin Hospital from April 2019 to April 2022 were selected. All patients underwent PCI and were followed up for 1 month. They were divided into good prognosis group and poor prognosis group according to whether adverse cardiovascular events (MACE) occurred. General data, cardiac ultrasound parameters[left ventricular wall thickness (LVPW), left atrial volume (LAV), cardiac output (CO), left ventricular ejection fraction (LVEF)], laboratory indicators [hemoglobin (Hb), neutrophil to lymphocyte ratio (NLR), interleukin-6 (IL-6), amyloid protein (SAA)] of the two groups were compared. Receiver operating characteristic (ROC) curve was used to analyze the prognostic value of each index in STEMI patients after PCI. Multivariate Logistic regression was used to analyze the risk factors of poor prognosis in STEMI patients after PCI. 【Results】The proportion of killip grade ≥Ⅲ and lesion number ≥2 in the good prognosis group was significantly lower than that in the poor prognosis group. Levels of LVPW, LAV, IL-6, SAA and NLR in the good prognosis group were significantly lower than those in the poor prognosis group, while scores of CO and LVEF were significantly higher than those in the poor prognosis group, with statistical significance (P<0.05). ROC curve analysis results showed that the area under the curve of LVPW, LAV, CO, LVEF, IL-6, SAA and NLR to evaluate the short-term prognosis of STEMI patients after PCI were 0.646, 0.772, 0.704, 0.822, 0.901, 0.818 and 0.729, respectively. Multivariate Logistic regression analysis showed that: killip grade ≥Ⅲ, number of lesions ≥2, LVPW≥6.835 mm, LAV≥56.495 mL, CO≤4.610 L/min, LVEF≤ 55.535%, IL-6≥5.665 ng/L, SAA≥4.890 mg/L and NLR≥3.005 were risk factors for poor short-term prognosis after PCI in STEMI patients (P<0.05).【Conclusion】LVPW, LAV, CO, LVEF, IL-6, SAA, NLR can affect the short-term prognosis of STEMI patients after PCI. Thus, the short-term prognosis of STEMI patients after PCI can be evaluated clinically by the above indicators.

Key words： ST Elevation Myocardial Infarction Angioplasty, Balloon, Coronary Ultrasonography Prognosis

Received: 09 February 2023

PACS:

R542.22

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	Articles by authors
	DOU Pan
	ZHOU Xueliang
	ZHENG Deliang

Cite this article:

DOU Pan,ZHOU Xueliang,ZHENG Deliang. Prognostic Value of Cardiac Ultrasound Parameters and Laboratory Indexes in Short-Term Prognosis of STEMI Patients after PCI[J]. JOURNAL OF CLINICAL RESEARCH, 2024, 41(4): 515-518.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2024.04.010 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2024/V41/I4/515

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