联动成像结合化学染色技术在大肠侧向发育型肿瘤分型中的应用价值

doi:10.3969/j.issn.1671-7171.2024.01.013

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Abstract 【Objective】 To explore the application of linked color imaging (LCI) combined with chemical staining technology in the classification of laterally spreading tumor of colorectal tumors (LST). 【Methods】 The examination images of 82 patients with colorectal tumors (89 lesions) diagnosed by LCI combined with chemical staining technology in our hospital were retrospectively analyzed, and the morphology of small pits on the surface of the lesions of the patients was evaluated. The characteristics of the lesions was predicted according to the morphological classification of small glandular canal opening (Pit) on the mucosal surface, And the Pit classification was compared with the pathologic results after endoscopic resection. 【Results】 The diagnosis of type Ⅰ, Ⅱ and Ⅱ-0 were mostly serrated lesions (SSP)/hyperplastic polyps (HP). The sensitivity, specificity and accuracy were 55.56%, 96.25% and 92.13%, respectively. The sensitivity, specificity and accuracy of type Ⅲ_S alone in the diagnosis of submucosal invasive carcinoma with an invasion depth ≥100 mm (SMd) were 20.00%, 98.81%, and 94.38%, respectively. The sensitivity, specificity and accuracy of the diagnosis of low-grade dysplasia (LGD)/high-grade dysplasia (HGD) for types Ⅲ_L and Ⅳ were 92.31%, 83.33%, and 89.89%, respectively. The sensitivity, specificity and accuracy of type Ⅴ_n alone in the diagnosis of SMd were 40.00%, 97.62%, and 94.38%, respectively. The sensitivity, specificity and accuracy of type Ⅴ_i and Ⅴ_n in the diagnosis of intramucosal carcinoma or submucosal invasive carcinoma with an invasion depth of less than 100 mm (m-SMs)/SMd were 86.67%, 97.30%, and 95.51%, respectively. The sensitivity, specificity and accuracy of type Ⅲ_S and type Ⅴ_n in the diagnosis of SMd were 60.00%, 96.43%, and 94.38%, respectively. 【Conclusion】 LCI combined with chemical staining can accurately and completely display the Pit shape of rectal mass, which makes it easier to assess whether the mass is neoplasm. And the predicted depth of tumor invasion of the has a high coincidence rate with the pathological diagnosis result.

Key words： Colorectal Neoplasms/DI Colonoscopy Immunohistochemistry

Received: 07 December 2022

PACS:

R735.35

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2024.01.013 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2024/V41/I1/47

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