超声引导下RFA及开放性手术对甲状腺微小乳头状癌患者甲状腺功能的影响

doi:10.3969/j.issn.1671-7171.2023.12.031

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Abstract 【Objective】To investigate the impact of ultrasound-guided radiofrequency ablation (RFA) and open surgery on thyroid function in patients with thyroid micropapillary carcinoma. 【Methods】A total of 90 patients with thyroid micropapillary carcinoma admitted to our hospital from March 2020 to February 2022 were selected and divided into an observation group and a control group according to different surgical procedures, with 45 cases in each group.The control group underwent open surgery, while the observation group underwent ultrasound-guided RFA treatment.Perioperative indicators were compared between the two groups, as well as thyroid function before and after surgery [thyroid-stimulating hormone (TSH), free triiodothyronine (FT₃), and free thyroxine (FT₄)].The levels of serum inflammatory factors [interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and C-reactive protein (CRP)] were compared before and after surgery, as well as the incidence of complications. 【Results】The operation time, intraoperative blood loss, hospitalization time, and hospitalization costs in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). The postoperative TSH level in the control group was significantly higher than that in the same group before surgery, while the FT₃ and FT₄ levels were lower than those in the same group before surgery, and the difference was statistically significant (P<0.05). The postoperative TSH level in the observation group was significantly lower than that in the same group before surgery, and the difference was statistically significant (P<0.05). The postoperative TSH level in the observation group was significantly lower than that in the control group, while the FT₃ and FT₄ levels were significantly higher than those in the control group, and the difference was statistically significant (P<0.05). The levels of serum IL-6, TNF-α, and CRP in both groups were higher than those before surgery, and the difference was statistically significant (P<0.05). The postoperative serum IL-6, TNF-α, and CRP levels in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). The incidence of complications in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). 【Conclusion】Ultrasound-guided RFA treatment for thyroid micropapillary carcinoma has less impact on thyroid function, with fewer postoperative complications and high safety.

Key words： Thyroid Neoplasms/SU Catheter Ablation Thyroid Function Tests

Received: 25 August 2022

PACS:

R736.1

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	Articles by authors
	CHEN Shanshan
	CAI Yongsheng
	HE Ning

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CHEN Shanshan,CAI Yongsheng,HE Ning. The Effect of Ultrasound-guided RFA and Open Surgery on Thyroid Function in Patients with Thyroid Micropapillary Carcinoma[J]. JOURNAL OF CLINICAL RESEARCH, 2023, 40(12): 1929-1932.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2023.12.031 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2023/V40/I12/1929

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