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| Efficacy of Traditional Chinese Medicine Fumigation in Treating Rheumatoid Arthritis and its Impact on Cytokines |
| YAN Jialing |
| Shandong Provincial Third Hospital,Jinan Shandong 250031 |
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Abstract 【Objective】To investigate the effect of traditional Chinese medicine fumigation on alleviating joint symptoms of rheumatoid arthritis (RA) patients and its impact on cytokines.【Methods】A total of 114 RA patients were randomly divided into two groups. Patients in the control group received methotrexate tablet treatment, while patients in the observation group received additional traditional Chinese medicine fumigation therapy. The changes in joint symptoms, Disease Activity Score of 28 joints (DAS28), erythrocyte sedimentation rate (ESR), cyclic citrullinated peptide antibodies (CCP-AB), C-reactive protein (CRP), rheumatoid factor (RF), α1-acid glycoprotein (α1-AGP), interleukin-35 (IL-35), and interleukin-17(IL-17) levels before and after treatment in both groups were compared. 【Results】There were no significant differences in any of the indices between the two groups before treatment (P>0.05). After treatment, the scores of joint symptoms and DAS28 in both groups significantly decreased compared to before treatment (P<0.05). These scores in the observation group were lower than those in the control group (P<0.05). Post-treatment, IL-35 levels in both groups significantly increased (P<0.05), while level of IL-35 in the observation group was higher than that in the control group (P<0.05).CCP-AB, ESR, CRP, RF, α1-AGP, and IL-17 levels significantly decreased after treatment in both groups, and levels of ESR and CCP-AB were significantly lower in the observation group compared to the control group (P<0.05). 【Conclusion】TCM fumigation can reduce the expression of ESR, CRP, and RF in RA patients through improving symptoms such as joint pain, swelling, tenderness, and functional impairment.
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Received: 28 December 2022
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2023, Vol. 40 
