不同时期急性脑梗死患者磁共振弥散张量成像特征及鉴别价值

doi:10.3969/j.issn.1671-7171.2023.10.006

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Abstract 【Objective】To explore the features and differences of magnetic resonance diffusion tensor imaging (DTI) in patients with acute cerebral infarction (ACI) at different time points. 【Methods】A total of 89 ACI patients treated in the two hospitals were selected and divided into the ultra-acute stage (onset ≤6 h) with 39 cases and the acute stage (6 h<onset≤3 d) with 50 cases based on the time of onset. The DTI parameters, including Fractional Anisotropy (FA), Mean Diffusion Coefficient (DCavg), and Isotropy (ISO) of lesion side and contralesional side were compared. Additionally, the values of lesion-side FA, DCavg, and ISO in diagnosing ultra-acute stage ACI were assessed. 【Results】 In the acute stage, the signal intensity on the FA image decreased and the brain white matter fibers were interrupted and destroyed, while no significant signal change was observed in the ultra-acute stage. In the ultra-acute stage, the signal on the DCavg image decreased and the brain white matter fibers were destroyed, whereas in the acute stage, brain white matter fibers were interrupted and reduced on the DCavg image. The FA value on the lesion side in the ultra-acute stage was higher than that in the acute stage, and the DCavg and ISO values were lower than in the acute stage (P<0.05). The DCavg value on the contralesional side in the ultra-acute stage was lower than in the acute stage, and the ISO value was higher (P<0.05). The DCavg values on the contralesional side in both the ultra-acute and acute stages were higher than on the lesion side, and the ISO values were lower (P<0.05). The FA value on the contralesional side in the acute stage was higher than on the lesion side (P<0.05). The Receiver Operating Characteristic (ROC) curve analysis showed that the Area Under the Curve (AUC) of the lesion-side FA value, DCavg value, ISO value alone and in combination for diagnosing ultra-acute stage ACI were 0.812, 0.842, 0.848, and 0.916 respectively. 【Conclusion】There are significant differences between the characteristics of DTI images in the acute stage and ultra-acute stage ACI patients. The DTI parameters, including FA, DCavg, and ISO values, can assist in diagnosing ACI staging, and their combined diagnostic efficacy is better.

Key words： Brain Infarction/DG Acute Disease Magnetic Resonance Imaging

Received: 30 December 2022

PACS:

R743.33

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	GAO Qiang
	HUANG Xiaoqi
	MA Xiaowei

Cite this article:

GAO Qiang,HUANG Xiaoqi,MA Xiaowei. Magnetic Resonance Diffusion Tensor Imaging Characteristics and Differentiation Value of Acute Cerebral Infarction Patients at Different Time Points[J]. JOURNAL OF CLINICAL RESEARCH, 2023, 40(10): 1459-1462.

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2023.10.006 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2023/V40/I10/1459

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