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| Analysis of Ocular Surface Changes in Patients with Refractive Error Treated with FS-LASIK and SMILE |
| LI Hong, ZHU Fei |
| Department of Ophthalmology,Yulin Traditional Chinese Medicine Hospital,Yulin Shaanxi 719000 |
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Abstract 【Objective】 To investigate the changes of ocular surface in patients with ametropia after femtosecond laser flap excimer laser laser in situ keratomileusis (FS-LASIK) and small incision stroma lens extraction (SMILE). 【Methods】A total of 38 patients with refractive errors who underwent FS-LASIK correction in our hospital from January 2021 to January 2022 were selected as the FS-LASIK group. In addition,38 patients with refractive errors who underwent SMILE correction in our hospital during the same period were selected as the SMILE group. The two groups were compared in terms of preoperative,postoperative 1 week,postoperative 1 month,postoperative 3 months,and postoperative 6 months,including the Eye Surface Disease Index (OSDI) questionnaire score,corneal fluorescence staining score,central lacrimal height (TMH),meibomian gland function score (LMS),and lipid layer thickness. 【Results】 Six months after surgery,the OSDI score of the FS-LASIK group was higher than that of the SMILE group (P<0.05),and the OSDI score increased at 1 week,1 month,and 3 months after surgery compared to those before surgery (P<0.05); The corneal fluorescein staining scores of both groups increased at 1 week and 1 month after surgery compared to before surgery (P<0.05); TMH in both groups increased at 1 week and 1 month after surgery compared to before surgery (P<0.05); There was no statistically significant difference in LMS and lipid layer thickness between the two groups before surgery,1 week after surgery,1 month after surgery,3 months after surgery,and 6 months after surgery (P>0.05). The lipid layer thickness of the two groups at 6 months after surgery decreased compared to that before surgery (P<0.05). 【Conclusion】 Both FS-LASIK and SMILE surgeries can have an impact on the ocular surface of ametropia patients,leading to dry eye symptoms. However,dry eye symptoms are more severe after FS-LASIK surgery.
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Received: 18 July 2022
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2023, Vol. 40 
