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| Predictive Value of HBP, sCD14-ST and IPS Scores for Urinary Sepsis after PCNL |
| ZHANG Xiao-rong, LI Wei |
| The First Hospital of Yulin,Yulin Shaanxi 719000 |
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Abstract 【Objective】 To investigate the predictive value of heparin binding protein (HBP), soluble CD14 subtype (sCD14-ST) and infection probability (IPS) scores on urinary sepsis after percutaneous nephrolithotomy (PCNL). 【Methods】 From January 2018 to January 2021, 44 patients with urinary sepsis after PCNL were selected as the observation group, and 44 patients without urinary sepsis after PCNL were selected as the control group. The clinical data, urinary HBP, serum sCD14-ST levels and IPS scores of the two groups were compared. The correlation between urinary HBP, serum sCD14-ST levels and IPS scores was analyzed. The influencing factors of urinary sepsis after PCNL were analyzed. The predictive value of each index for urinary sepsis after PCNL was evaluated. 【Results】 The positive rate of urine culture before operation in the observation group was higher than that in the control group, the operation time was longer than that in the control group, and the urine HBP, serum sCD14-ST levels and IPS scores were higher than those in the control group(P<0.05). Pearson correlation analysis showed that urine HBP, serum sCD14-ST levels were positively correlated with IPS scores (r=0.608, 0.534, P<0.05). Logistic regression analysis showed that positive urine culture before operation, operation time, urine HBP, serum sCD14-ST, IPS score were the influencing factors of urinary sepsis caused by PCNL (P<0.05). The AUC of urine HBP, serum sCD14-ST and IPS scores for predicting urinary sepsis after PCNL was 0.909, 95%CI was 0.828～0.960, sensitivity was 95.45%, specificity was 75.00%, which was significantly higher than those predicted by the three alone.【Conclusion】Urine HBP, serum sCD14-ST and IPS scores are the influencing factors of urinary sepsis after PCNL. The combined detection can be used as an important method to predict the occurrence of urinary sepsis.
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Received: 22 August 2021
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2022, Vol. 39 
