Abstract 【Objective】To investigate the effect of uvulopalatopharyngoplasty (UPPP) and continuous positive airway pressure (CPAP) in the treatment of patients with obstructive sleep apnea hypopnea syndrome (OSAHS) and laryngopharyngeal reflux (LPR). 【Methods】A total of 79 patients with OSAHS and LPR were randomly divided into the UPPP group (n=42) and the CPAP group (n=37) according to the random number table method. Patients Aeration index (AHI), snoring index, upright Ryan index, supine Ryan index, reflux symptom index (RSI) score, the reflux symptom index (RSI) and the reflux fineling scores (RFS) before and mean oxygen saturation were recorded and compared between the two groups.【Results】OSAHS patients with LPR had severe daytime sleepiness, sleep efficiency reduction, moderate and severe sleep apnea, and obvious throat reflux symptoms before treatment. After treatment, AHI, snoring index, Ryan index, Ryan index in supine position, RSI and RFS in UPPP and CPAP group were significantly lower than those before treatment; And the mean blood oxygen saturation was significantly higher than that before treatment (P<0.05). Compared with CPAP group, the Ryan index in supine position, RSI and RFS in UPPP group were significantly lower than those in CPAP, and the difference was statistically significant (P<0.05). 【Conclusion】Both UPPP and CPAP are helpful in the treatment of OSAHS with laryngopharyngeal reflux. Compared to CPAP, UPPP alleviated the symptoms of LPR better.
ZHANG Xiao-ping,CHEN Gui,ZHANG Ming. Application of Uvulopalatopharyngoplasty and Continuous Positive Pressure Ventilation in the Treatment of OSAHS with Laryngopharyngeal Reflux[J]. JOURNAL OF CLINICAL RESEARCH, 2022, 39(9): 1288-1290.
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2022, Vol. 39 
