Abstract 【Objective】To investigate the relationship of serum C-reactive protein (CRP),procalcitonin (PCT),lactate dehydrogenase (LDH) and cystatin C (cys C) levels with kidney injury after bee sting.【Methods】The clinical data of 130 patients with bee stings were retrospectively analyzed. According to whether acute kidney injury (AKI),patients were divided into the AKI group (n=38) and the non-AKI group (n=92).At admission,baseline information was collected and laboratory indicators [platelet count (PLT),CRP,PCT,LDH,cys C] were measured. The value of serum CRP,PCT,LDH and cys C in predicting AKI in patients with bee sting was analyzed by ROC. The difference information between the two groups was included in multivariate Logistic regression analysis and quantitative assignment was performed to identify the influencing factors of AKI in patients with bee sting.【Results】There were no significant differences in gender,age,bee sting site,associated diseases,bee sting time and PLT level between the two groups (P>0.05).The proportion of bee stings and hospital admission time≥6 h after injury in the AKI group was significantly higher than that in the non-AKI group,and the levels of serum CRP,PCT,LDH and cys C were significantly higher in the AKI group than those in the non-AKI group,with statistical significance (P<0.05).ROC analysis showed that CRP≥6.285 mg/L,PCT≥1.570 ng/mL,LDH≥1482.175 U/L and cys C≥1.430 mg/L could be used to predict AKI in bee sting patients (P<0.05).Multiple Logistic regression analysis confirmed that wasp species of sting,hospital admission time and serum levels of CRP,PCT,LDH and cys C were significant influencing factors of AKI in patients with bee sting injury (P<0.05).【Conclusion】Serum levels of CRP,PCT,LDH and cys C were significant influencing factors of AKI in bee sting patients. The occurrence of AKI can be predicted when CRP≥6.285 mg/L,PCT≥1.570 ng/mL,LDH≥1482.175 U/L and cys C≥1.430 mg/L showed up.
CHEN Shang-kou,HUANG Ren-chun,SHI Shan-qiu. Relationship of Serum CRP,PCT,LDH and cys C Levels with Kidney Injury after Bee Sting[J]. JOURNAL OF CLINICAL RESEARCH, 2022, 39(8): 1157-1160.
2022, Vol. 39 
