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Influencing Factors of Clinicopathological Characteristics and Recurrence Risk of Vocal Cord Leukoplakia |
BAI Feng-bo, CHE Na |
Department of Otorhinolaryngology, Xi'an Aerospace General Hospital, Xi'an Shaanxi, 710100 |
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Abstract 【Objective】 To explore the influencing factors of clinicopathological characteristics high clinical recurrence risk of vocal cord leukoplakia.【Methods】A retrospective analysis of 96 patients with vocal cord leukoplakia treated in our hospital was used as the observation group. The patients were divided into high-risk groups (n=15) and low-risk groups (n=81) according to their pathological types. According to the recurrence, patients were divided into recurrence group (n=17) and non-recurrence group (n=79). In the same time period, 89 volunteers who had a healthy physical examination in our hospital were selected as the control group. Clinical data were collected and analyzed. 【Results】 (1) There was no significant difference between the observation group and the control group in the proportion of males, age> 60 years old, general hospital depression scale (HADD) score> 1 point, and general hospital anxiety and depression scale (HADA) score> 1 point(P>0.05). However, the proportion of smoking, drinking, reflux symptom index (RSI)>10, reflux sign score (RFS)>6, and overuse of voice in the observation group was significantly higher than that of the control group (P<0.05). (2) The proportion of the high-risk group with age >60 years old and scattered leukoplakia was significantly higher than that of the low-risk group.( 3) The proportion of the recurrence group with age> 60 years old and scattered leukoplakia in the recurrence group was significantly higher than that in the non-recurrence group; the differences were statistically significant (all P<0.05). 【Conclusion】Smoking, drinking and overuse of voice are the influencing factors of vocal leukoplakia. The elderly patients with leukoplakia are at high risk of recurrence.
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Received: 20 October 2020
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