氯化琥珀胆碱对快速诱导气管插管后中心静脉血氧饱和度的影响

doi:10.3969/j.issn.1671-7171.2021.10.007

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Abstract 【Objective】To compare the effects of depolarized muscle relaxants and non depolarized muscle relaxants on superior vena cava oxygen saturation. 【Methods】 A total of 50 patients with lower abdominal non endoscopic surgery and unilateral upper and lower limb elective surgery for non traumatic fractures were randomly divided into observation group and control group, with 25 cases in each group. Endotracheal intubation was rapidly induced by succinylcholine chloride (1.2mg/kg) and atracurium CIS benzenesulfonate (0.25 mg/kg), respectively. The superior vena cava blood was collected at the time of entry (T₀), 1 min (T₁), 3 min (T₂), 10 min (T₃) after endotracheal intubation and 10 min (T₄) after operation for blood gas analysis. The changes of superior vena cava oxygen partial pressure (PcvO₂), superior vena cava oxygen saturation (ScvO₂), blood glucose (GLUcv) and lactic acid (LACcv) were compared between the two groups. 【Results】 There was no significant difference in PcvO₂,ScvO₂ ,GLUcv,LACcv between the two groups at T₀ (P>0.05); At T1 , PcvO₂ and ScvO₂ in the control group were higher than those in the observation group (P<0.05). The incidence of mild cough, limb movement and prolonged retention time at the tracheal inlet in the control group was 40%, which was significantly higher than 8% in the observation group (χ²=8.47, P<0.05). 【Conclusion】Compared with atracurium CIS benzenesulfonate, low-dose succinylcholine induced rapid endotracheal intubation has better endotracheal intubation conditions, effectively inhibits the choking reflex caused by endotracheal intubation, and the indexes of circulation, PcvO₂ and ScvO₂ after endotracheal intubation are more stable, which is conducive to the balance of tissue oxygen supply and demand.

Key words： Intubation, Intratracheal Succinylcholine/TU Oximetry Catheterization, Central Venous

Received: 16 June 2021

PACS:

R605.973

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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2021.10.007 OR http://journal07.magtech.org.cn/yxlcyj/EN/Y2021/V38/I10/1466

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