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| Effect of Autologous Blood Transfusion on PT, APTT and TT in Patients with Traumatic Brain Injury |
| YU Mao-wen |
| West China Hospital Sichuan University Jintang Hospital,chengdu 610400, Sichuan |
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Abstract 【Objective】 To investigate the effect of autologous blood transfusion on coagulation function in patients undergoing traumatic surgery. 【Methods】 100 patients with traumatic brain injury who were required to undergo surgical treatment and need blood transfusion in our hospital were selected as the study subjects. The randomized digital table method was divided into 50 cases in the study group and the control group. The study group collected surgical bleeding and returned. Allogeneic blood was added when blood transfusion was insufficient; allogeneic blood transfusion was only used in the control group; prothrombin time (PT), activated partial thrombin time (APTT), and thrombin time were compared between the two groups before surgery, 1 day after surgery, and 3 days after surgery. (TT), plasma D-dimer (DD), fibrinogen (FIB), pH, hemoglobin (Hb), hematocrit (Hct), platelet (PLT). 【Results】 After repeated measures of variance analysis, the PT, APTT, TT, FIB, and DD values of the study group and the control group were compared at three time points before, 1 day, and 3d after surgery. Statistically significant (P<0.05); the PT, APTT, and TT 、 FIB values in the study group were lower than those in the control group (P<0.05), and the DD values were higher than the control group (P<0.05). P<0.05); The pH, Hct, and PLT measurements of the study group and the control group were statistically significant at the three time points before, 1 day, and 3d after surgery(P<0.05); The measured values of pH, Hct and PLT in the study group were higher than those in the control group at 1 day after operation and 3 days after operation (P<0.05). The complication rate of the study group was 4.00% lower than that of the control group. 16.00%, the difference was statistically significant (P<0.05). 【Conclusion】 Autologous blood transfusion in patients with craniocerebral trauma surgery is beneficial to reduce the impact on coagulation function and has high safety.
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Received: 10 October 2019
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2021, Vol. 38 
