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| Observation on Curative Effect of Baihua Sandi Granule in Treating 168 Cases of Chronic Pelvic Inflammatory Disease |
| DAI Ting-ting, YAN Min, ZHU Ying, et al |
| Department of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, China |
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Abstract 【Objective】 To study the curative effect of Baihua Sandi Granules on chronic pelvic inflammatory disease.【Methods】A total of 328 patients with chronic pelvic inflammation in our hospital from 2014 to 2018 were retrospectively analyzed. Among them, 168 patients in the observation group were treated with Baihua Sandi granules, and 160 patients in the control group were treated with conventional treatment. The total response rate, changes of B-ultrasound, changes of interleukin-6 (IL-6), tumor necrosis factor (TNF-α) and C-reactive protein (CRP) inflammatory indexes were compared between 2 groups after treatment. 【Results】 The total effective rate of the observation group was 92.8%, and the total effective rate of the control group was 85.6%, and there was statistical difference between the two groups (P<0.05). After treatment, the recovery rate of B-mode ultrasonography was 77.8% in the observation group and 76% in the control group. There was no statistical difference between the two groups. After treatment, there were significant differences in IL-6, TNF-α and CRP between the two groups (P<0.05).【Conclusion】Baihua Sandi granules can effectively improve the symptoms of patients with chronic pelvic inflammation and regulate the level of inflammatory factors, which is worthy of application and promotion.
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Received: 25 November 2020
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[1] 王宜民,王秀民,解俊霞,等. 近5年中西医结合治疗慢性盆腔炎临床研究进展[J].河北中医,2013,35(10):1580-1582.
[2] 蔡艳,董莉,叶玉妹,等. 慢性盆腔炎诊治进展[J].医学美学美容(中旬刊),2015(3):653.
[3] 鲍岩岩,刘艳,唐晓波,等. 白花蛇舌草水提取物对大鼠细胞色素P450 1A2 亚型的影响[J].哈尔滨医科大学学报,2007,41(1):4-7.
[4] 胡莹,梅全喜. 广东地产药材入地金牛的药理作用及临床应用研究进展[J].今日药学,2011,21(3):142-145.
[5] 陈倩玲,程江虹,叶宛琼,等. 入地金牛酊导入配合激光治疗慢性盆腔炎的疗效观察[J].中华临床医学研究杂志,2003(12):11591-11592.
[6] 卫琮玲,闫杏莲,柏李,等. 地骨皮的镇痛作用[J].中草药,2000,31(9):688-689.
[7] 魏秀丽,梁敬钰. 地骨皮化学成分的研究[J].中国药科大学学报,2002,33(4):271-273.
[8] 黄丽. 药效学方法优化白花三地提取工艺的实验研究[D].中南大学,2010.
[9] 雷鹏,刘韶,李新中,等. 正交试验法优选白花三地颗粒的水提工艺[J].中国医院药学杂志,2008,28(23):2001-2004.
[10] 王冬梅. 慢性盆腔炎治疗进展[J].现代医药卫生,2012,28(13):2018-2020.
[11] 邱若旗. 中西医诊治慢性盆腔炎[J].实用妇科内分泌电子杂志,2019,6(25):9, 42.
[12] 黄义. 白花三地提取工艺的研究[D].中南大学,2009.
[13] 孙培文. 白花三地颗粒制备工艺与质量标准研究[D].中南大学,2011.
[14] 雷鹏,黄义,李新中,等. 白花三地复方不同方法提取液对小鼠耳廓肿胀作用的比较研究[Z].衡阳:2009,342-345. |
| [1] |
. [J]. JOURNAL OF CLINICAL RESEARCH, 2021, 38(3): 449-452. |
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2021, Vol. 38 
