医学临床研究
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JOURNAL OF CLINICAL RESEARCH  2020, Vol. 37 Issue (10): 1504-1507    DOI: 10.3969/j.issn.1671-7171.2020.10.019
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Risk Factors of Early Mortality in Patients with Severe Left Ventricular Dysfunction after Cardiac Surgery
WANG Su, HUANG Jian-chang, ZANG Wang-fu, et al
The Tenth People's Hospital Affiliated to Tongji University, Shanghai 200072
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Abstract  【Objective】 To investigate the predictors of early postoperative mortality in patients with severe left ventricular dysfunction undergoing cardiac surgery. 【Methods】 A total of 106 eligible cardiac surgeries performed by the same surgeon from 2012 to 2019 were retrospectively analyzed. All patients were divided into death group (n=14) and survival group (n=92) according to the survival status of perioperative patients. Univariate and multivariate analysis were performed. 【Results】 Univariate analysis showed that age, body fat mass index (BMI), white blood cell count (WBC), C-reactive protein (CRP), N-terminal pro brain natriuretic peptide (NT proBNP) and operation mode were significantly associated with early postoperative death (P<0.1). Combined with previous literature, creatinine (SCr) and troponin T (cTnT) were also included in the multivariate logistic regression analysis. Finally, it was found that SCr, WBC, cTnT and operation mode were independent risk factors for early postoperative death in patients with low ejection fraction (all OR > 1, P<0.05).【Conclusion】 SCr, WBC, cTnT and surgical methods were independent risk factors for early postoperative death in patients with low ejection fraction. These patients should be fully evaluated before operation, and timely anti-inflammatory, myocardial nutrition and other treatments should be taken to avoid operation in acute myocardial infarction stage.
Key wordsVentricular Function      Left/SU      Cardiac Surgical Procedures      Risk Factors     
Received: 15 May 2020     
PACS:  R541.42  
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http://journal07.magtech.org.cn/yxlcyj/EN/10.3969/j.issn.1671-7171.2020.10.019     OR     http://journal07.magtech.org.cn/yxlcyj/EN/Y2020/V37/I10/1504
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