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| Application of Uterine Artery Embolization Combined with Methotrexate, Ethacridine and Mifepristone in Induction of Labor in Late Complete Placenta Previa |
| WANG Jing, LU Ying, YANG Xue-qin |
| Department of Obstetrics and Gynecology,Liangshan Prefecture Integrated Traditional Chinese and Western Medicine Hospital,Liangshan, Sichuan,615000 |
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Abstract 【Objective】To investigate the effect of uterine artery embolization combined with methotrexate, ethacridine and mifepristone in induced labor of pregnant women with complete placenta previa. 【Methods】The clinical data of 93 pregnant women with complete placenta previa induced labor in our hospital from March 2014 to March 2018 were retrospectively analyzed. According to the different treatment methods, they were divided into control group and observation group. The control group was induced by bilateral uterine artery embolization combined with ethacridine and mifepristone; the observation group was induced by methotrexate on the basis of the control group. The time of labor, the amount of bleeding during labor, the amount of postpartum hemorrhage, hospitalization time, lochia time, menstrual recovery time, success rate of induced labor, hysterectomy rate, curettage rate and postoperative complications were compared between the two groups. 【Results】The amount of intrapartum hemorrhage, postpartum hemorrhage and hospitalization time in the observation group were significantly lower than those in the control group (P<0.05); however, there was no significant difference in the labor time, lochia duration, menstrual recovery time, induced labor success rate, hysterectomy rate and uterine curettage rate between the two groups (P>0.05). The total incidence of postoperative complications in the observation group was 23.33%, which was not significantly different from 24.24% in the control group (P>0.05). 【Conclusion】Uterine artery embolization combined with methotrexate, ethacridine and mifepristone in the induction of labor of late complete placenta previa can reduce the amount of bleeding during labor and postpartum, shorten the hospitalization time, and does not increase the incidence of adverse reactions and complications, which is worthy of clinical application.
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Received: 27 January 2019
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2020, Vol. 37 
