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| Effects of Nabocone Injection on Sedation, Analgesia and Negative Emotions after Cesarean Section |
| LI Shi-hong, DENG Hong-yan, MOU Jun-jie |
| Department of anesthesiology, Haiyang Peoples Hospital, Shandong Province,265100 |
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Abstract 【Objective】 To explore the effects of nabocone hydrochloride on sedation, analgesia and negative emotions after cesarean section in women. 【Methods】 A total of 128 patients of full-term pregnant women who received cesarean section in our hospital were selected and randomly divided into two groups. There were 64 cases in the observation group who received intravenous injection of nabocone hydrochloride, while 64 cases in the control group received intravenous sufentanil analgesia. The sedative and analgesic effects of the two groups were observed and compared. The degree of postpartum depression of the two groups were measured and compared as well, while the total incidence of adverse reactions was calculated. 【Results】 The analgesic scores of 6h, 12h and 24h in the observation group were significantly lower than those in the control group; and the sedation score in the observation group was also lower than that in the control group. The difference between the two groups was significant (P<0.05). There was no significant difference in the antenatal depression score between the two groups (P>0.05). The postpartum depression score of the observation group 3 days after delivery in the observation group was significantly lower than that in the control group (P<0.05). The total postpartum depression rate in the observation group was7.81% which was significantly lower than that of the control group (23.44%, P<0.05). The incidence of adverse reactions in the observation group was 11.76% (8/64), which was significantly lower than that in the control group (59.38%, 38/64). The difference between the two groups was statistically significant (P<0.05). 【Conclusion】 Nabocone hydrochloride injection has a good effect on postoperative analgesia and sedation in cesarean parturients, the possibility of postpartum depression and the incidence of adverse reactions are low. It is suitable for clinical popularization.
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Received: 29 May 2018
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2020, Vol. 37 
