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| Etiological Characteristics of Infection in Elderly Patients with Cervical Cancer after Radical Resection |
| WANG Yu, ZENG Yan |
| Department of Obstetrics and Gynecology, Affiliated Hospital of Chengdu University, Chengdu 610081, Sichuan |
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Abstract 【Objective】To analyze the etiological characteristics of infection in elderly patients with cervical cancer after radical resection. 【Methods】A total of 163 elderly patients with cervical cancer who underwent surgical resection in Chengdu University Hospital from March 2014 to October 2018 were selected for the study. The incidence of postoperative infection, pathogenic characteristics and risk factors of postoperative infection were analyzed. 【Results】The incidence of postoperative infection was 28.22% (46/163), among which urinary tract infection (43.48%), surgical incision infection (23.91%) and vagina infection (10.87%) ranked the top three. A total of 57 pathogenic bacteria were detected, which contained 27 gram-negative bacteria (47.39%), 23 gram-positive bacteria (40.35%) and 7 fungi (12.28%). The top two pathogens were Escherichia coli (21.05%) and Staphylococcus aureus (15.79%). The susceptibility of Escherichia coli to imipenem, rifampicin and erythromycin was high (< 10%), while the resistance to sulfamethoxazole, piperacillin, levofloxacin and tetracycline was more than 80%. Staphylococcus aureus was highly sensitive to imipenem without any drug resistance, while its resistance to rifampin, penicillin G and levofloxacin was more than 70% and resistance to ceftriaxone, tetracycline and sulfamethoxazole was more than 40%. Single factor and logistic Univariate and multivariate logistic regression analysis showed that operation time ≥3h, urinary catheter retention time ≥14d, antibiotics usage ≥3 kinds, postoperative chemotherapy and anemia were independent risk factors for postoperative infection (P<0.05). 【Conclusion】The incidence of infection is high in the elderly patients with cervical cancer after radical resection. The main pathogens are Escherichia coli and Staphylococcus aureus showing high resistant to common antibiotics. In practical clinical work, antibiotics should be selected reasonably according to the results of drug resistance analysis, so relevant preventive measures should be taken against the risk factors of postoperative infection.
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Received: 15 March 2019
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2020, Vol. 37 
