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| Analysis of Cardiovascular Malformations and Pregnancy Outcomes in 112 Fetuses of Single Umbilical Artery |
| LI Qiao-rong, LONG Xiang-dang, YAO Sui,et al |
| Department of Medical Ultrasound,The First Affiliated Hospital of Hunan Normal University/Hunan Provincial People's Hospital,Hunan 410005,China |
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Abstract 【Objective】To investigate the clinical features of single umbilical artery (SUA) with cardiovascular malformations. 【Methods】A total of 112 fetuses with SUA were retrospectively analyzed. Clinical data and ultrasound images were collected to investigate complication with cardiovascular malformations and pregnancy outcomes. 【Results】Among the 112 SUA patients, simple SUA occurred in 80 cases(71.4%) and SUA complicated with other structural malformations were seen in 32 cases (28.6%),of which 25 cases(25/32,22.3%) were combined with cardiovascular malformations including 18 cases of severe complex malformations. No abnormal chromosome findings were shown in all 25 cases of SUA with cardiovascular malformations. However,20 cases were induced labor and 5 live births (2 cases of ventricular septal defect and 3 cases of ventricular septal defect with left superior vena cava were diagnosed by prenatal and postnatal ultrasound follow-up). The cardiovascular malformations in the top three places were ventricular septal defect (17/25, 68%), persistent left superior vena cava (6/25, 24%) and persistent arterial trunk (5/25, 20%). 【Conclusions】The most common malformations in SUA is cardiovascular malformation, which is so complicated types and poor prognosis. The diagnosis of fetal structural abnormalities during pregnancy, especially in the second trimester, is important for early intervention and reduction of birth defects.
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Received: 15 May 2019
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[1] 伍霞芳,黄卫飞,洪露曦.超声诊断单脐动脉与胎儿先天异常关系的研究[J].中国妇幼保健,2012,27(30):4795-4797.
[2] 段灵敏,郭燕丽,邓凤莲,等.产前超声诊断胎儿单脐动脉[J].中国医学影像学杂志,2014,22(4):278-281.
[3] Murphy-Kaulbeck L,Dodds L,Joseph KS,et al.Single umbilical artery risk factors and pregnancy outcomes[J].Obstet Gynecol,2010,116(4):843-850.
[4] Martínez-Payo C,Cabezas E,Nieto Y,et al.Detection of single umbilical artery in the first trimester ultrasound: its value as a marker of fetal malformation[J].Biomed Res Int,2014,2014(2014):548729.
[5] Ashwal E, Melamed N,Hiersch L,et al.The impact of isolated single umbilical artery on labor and delivery outcome [J].Prenat Diagn,2014,34(6):581-585.
[6] 姜燕,佘志红,林琪,等.彩色多普勒超声在产前诊断单脐动脉的临床价值[J].中国超声诊断杂志,2005,6(1):48-50.
[7] Persutte WH, Hobbins J. Single umbilical artery: a clinical enigma in modern prenatal diagnosis[J].Ultrasound Obstet Gynecol,1995,6(3):216-229.
[8] Peckham CH,Yerushalmy J. Aplasia of one umbilical artery: Incidence by race and certain obstetic factors [J].Obstet Gynecol,1965,126:359-366.
[9] Joó JG,Beke A,Papp Z, et al.Single umbilical artery in fetopathological investigations [J].Pathol Res Pract,2008,204(11):831-836.
[10] 郝晓艳,何怡华,张烨,等.产前诊断单脐动脉及其合并心血管畸形的意义[J].心肺血管病杂志,2015,34(9):706-708. |
| [1] |
. [J]. JOURNAL OF CLINICAL RESEARCH, 2019, 36(7): 1400-1401. |
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2019, Vol. 36 
