缺血后处理对STEMI患者PCI术后心肾脏功能的影响

doi:10.3969/j.issn.1671-7171.2018.09.008

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Abstract 【Objective】 To investigate and discuss the effect of ischemic post-conditioning on the cardio-renal function in patients with STEMI (ST-segment elevation myocardial infarction) after PCI (percutaneous coronary intervention). 【Methods】 A total of 106 patients with myocardial infarction from Jan 2014 to Jan 2016 in our hospital were randomly divided into the observation group (53 cases) and the control group (53 cases). Patients in the control group received PCI procedure directly.The observation group was treated with ischemic post-conditioning before performing PCI. The cardio-renal function levels and rate of major adverse cardiovascular events were compared in the two groups. 【Results】 The rate of electrocardiogram ST-segment decline immediately after the procedure was significantly higher in the observation group than in the control group (P<0.05). WMIS, MIS and the incidence of reperfusion arrhythmia during the procedure were significantly lower in the observation group than in the control group (P<0.05).The rate of contrast-induced renal impairment (CI-AKI) serum creatinine value 48 hours after the procedure, and the rate of one-year major adverse cardiovascular events (MACE) were significantly lower in the observation group than in the control group (P<0.05). 【Conclusion】 Ischemic post-conditioning can effectively alleviate myocardial ischemia-reperfusion injury after PCI in patients with STEMI, reduce the incidence of postoperative contrast nephropathy and adverse cardiovascular events, and have a good protective effect on the heart and kidney function of patients.

Key words： Myocardial Infarction Acute Disease Angioplasty Transluminal Percutaneous Coronary

Received: 10 April 2018

PACS:

R542.22

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	LI Lin-xia
	WANG Ju-hua
	TIAN Xiao-dong

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LI Lin-xia,WANG Ju-hua,TIAN Xiao-dong. Effect of Ischemic post-conditioning on Cardio-renal Function in Patients with Myocardial infarction (STEMI) after PCI[J]. JOURNAL OF CLINICAL RESEARCH, 2018, 35(9): 1690-1692.

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http://www.jcr.net.cn/EN/10.3969/j.issn.1671-7171.2018.09.008 OR http://www.jcr.net.cn/EN/Y2018/V35/I9/1690

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