Clinical Efficacy of Escitalopram Combined with Electrical Stimulation Aversion Therapy on Refractory Obsessive-compulsive Disorder:31 Cases of Clinical Report
ZHENGLin, TIANYue, CHENGAO-bo, et al
Kailuan Mental Health Center Affiliated to North China University of Science and Technology,Tangshan 063000
Abstract 【Objective】 To investigate the effect of escitalopram combined with electrical stimulation aversion therapy on refractory obsessive-compulsive disorder. 【Methods】 From January 2017 to January 2018, 62 cases of patients with refractory obsessive-compulsive disorder were studied in our hospital. According to the simple random method, they were divided into two groups, 31 cases in each group; the control group was treated with escitalopram, and the observation group was treated with escitalopram combined with electric stimulation aversion therapy. The therapeutic effects, the Yale-Brown compulsion scale, HAMA scale score, and the incidence of adverse reactions during treatment were compared between the two groups. 【Results】 The effective rate of the control group was 74.29%, the effective rate of the observation group was 93.55%, and the effective rate of the observation group was higher than that of the control group (P<0.05). The scores of the Yale-Brown and HAMA scales in the two groups were lower than those before the treatment (P<0.05), and the score of the Yale-Brown compulsion scale in the observation group was lower than that of the control group (P<0.05), and there was no statistical difference between the two groups after the treatment (P>0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Escitalopram combined with electrical aversion therapy is effective in treating obsessive-compulsive disorder. It can effectively improve the clinical symptoms of patients with high safety.