艾司西酞普兰联合电刺激厌恶疗法对难治性强迫症31例临床观察

doi:10.3969/j.issn.1671-7171.2018.08.028

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Abstract 【Objective】 To investigate the effect of escitalopram combined with electrical stimulation aversion therapy on refractory obsessive-compulsive disorder. 【Methods】 From January 2017 to January 2018, 62 cases of patients with refractory obsessive-compulsive disorder were studied in our hospital. According to the simple random method, they were divided into two groups, 31 cases in each group; the control group was treated with escitalopram, and the observation group was treated with escitalopram combined with electric stimulation aversion therapy. The therapeutic effects, the Yale-Brown compulsion scale, HAMA scale score, and the incidence of adverse reactions during treatment were compared between the two groups. 【Results】 The effective rate of the control group was 74.29%, the effective rate of the observation group was 93.55%, and the effective rate of the observation group was higher than that of the control group (P<0.05). The scores of the Yale-Brown and HAMA scales in the two groups were lower than those before the treatment (P<0.05), and the score of the Yale-Brown compulsion scale in the observation group was lower than that of the control group (P<0.05), and there was no statistical difference between the two groups after the treatment (P>0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). 【Conclusion】 Escitalopram combined with electrical aversion therapy is effective in treating obsessive-compulsive disorder. It can effectively improve the clinical symptoms of patients with high safety.

Key words： Compulsive Personality Disorder/TH Pharmaceutical Preparations Electric Stimulation Therapy

Received: 28 June 2018

PACS:

R749.75

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http://www.jcr.net.cn/EN/10.3969/j.issn.1671-7171.2018.08.028 OR http://www.jcr.net.cn/EN/Y2018/V35/I8/1542

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