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| Factors Influencing Survival of Patients with Hilar Cholangiocarcinoma |
| FANFang-yong, CHANGHui-xian, YULian-jun, et al |
| The Huanghua Municipal People's Hospital,Huanghua, Hebei Province, 061100 |
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Abstract 【Objective】 To investigate the survival status and related factors of patients with hilar cholangiocarcinoma(HC).【Methods】 The clinical data of 93 patients with HC admitted in our hospital from June 2011 to June 2012 were analyzed retrospectively. The general data of all patients were collected and followed up. The factors affecting the survival status of HC patients were analyzed by univariate and multivariate analysis.【Results】 The 1-year, 3-year and 5-year survival rates of patients with radical resection were 84.78%, 45.65% and 23.91% respectively, which were significantly higher than those of patients with the palliative treatment group (P<0.05).There was no significant difference in 5-year survival rate among HC patients of different genders and ages (mean P>0.05). The 5-year survival rates of HC patients with different TNM stages, surgical schemes, preoperative carcinoembryonic antigen levels and the highest preoperative serum total red gallstone levels were significantly different (P<0.05). TNM stage Ⅲ~Ⅳ, palliative treatment regimen, preoperative carcinoembryonic antigen level higher than 5.0 ng/mL and preoperative highest serum total erythrocholine level above 342.0 mol/L were independent risk factors for 5-year survival rate of HC patients (P<0.05).【Conclusion】 The long-term survival status of patients with HC undergoing radical resection is good. TNM stage Ⅲ~Ⅳ, palliative therapy, preoperative carcinoembryonic antigen level higher than 5.0 ng/mL and preoperative highest serum total erythrocholine level above 342.0 mol/L are independent risk factors for poor long-term survival of patients.
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Received: 09 March 2018
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2018, Vol. 35 
