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| Clinical Efficacy of Continuous Vena-venous Hemofiltration Combined with Invasive Mechanical Ventilation on Refractory Heart Failure (24 Cases of Report) |
| ZENG Yi-qian, ZENG Wei-zhong, PENG Su-na, et al |
| Zhuzhou Central Hospital, Hunan, Zhuzhou 412007, China |
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Abstract 【Objective】To explore the clinical effect of continuous Vena-venous hemofiltration (CVVH) combined with invasive mechanical ventilation for refractory heart failure.【Methods】A total of 46 patients with refractory heart failure were selected in the ICU of the Zhuzhou Center Hospital from March 2015to April 2017, and they were divided into observation group ( n = 24) and control group ( n = 22 ) by using the random number table method. The control group was treated with routine therapy and invasive mechanical ventilation, while the observation group was treated with continuous hemofiltration CVVH on the basis of the control group. The improvement of cardiac function, renal function and related respiratory function was compared between the two groups before and after treatment.【Results】After treatment, the improvement of left ventricular ejection fraction, cardiac output and oxygenation index in the observation group was significantly better than that in the control group, and the levels of blood urea nitrogen and creatinine in the observation group were lower than those in the control group (P<0.05). Compared with the control group, the number of B-line ultrasound in the observation group was significantly lower than that in the control group (P<0.05), and the time of invasive mechanical ventilation was shorter than that in the control group, the difference was statistically significant (P<0.05).【Conclusion】For refractory heart failure, invasive mechanical ventilation combined with continuous hemofiltration therapy can improve the heart and kidney function of patients, remove the machine early, and have high clinical application value.
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Received: 21 November 2017
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2018, Vol. 35 
