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| Effect of Butorphenol Combined with Midazolam and Pethidine Combined with Promethazine on Relieving Gastric Stretch in Patients with Gastric Perforation Repair |
| ZHANG Guo-yan, CHEN Xiao-fang |
| Anesthesiology Department of the Second People's Hospital in Kashi region, Xinjiang , Xinjiang Kashi 844000 |
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Abstract 【Objective】To investigate the effect of butorphenol combined with midazolam and pethidine combined with promethazine on relieving gastric stretch in patients with gastric perforation repair.【Methods】Among 100 patients undergoing gastric perforation repair, 50 patients were treated with butorphen and midazolam intravenously in 5 minutes before incision after satisfactory epidural anesthesia. The other 50 cases were given pethidine plus promethazine intravenously as group B. The changes of heart rate, mean arterial pressure (MAP), pulse oxygen saturation (SpO2), Ramsay sedative score and the degree of gastric retraction were compared between the two groups.【Results】Compared with T0 before treatment, HR, MAP, SpO2at T1~T4after treatmentin the group A were stable (P>0.05), and HR and MAP in the group B were fluctuating significantly (P<0.05), while SpO2was stable (P>0.05).There were no significant difference between the two groups compared Ramsay scores at T1and T2 (P<0.05), while at T3and T4in the group A were significantly higher than those in the group B (P<0.05).The excellent and good rate of in the group A (86%) was significantly higher than that in the group B (70%) (P<0.05).【Conclusion】Midazolam combined with Bhutto enphol can significantly reduce the effect of gastric traction in the operation, and its effect is better than piperidine + promethazine.
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Received: 26 February 2017
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2018, Vol. 35 
