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Efficacy Comparison of Four Schemes for Treatment of Cesarean Scar Pregnancy |
LV Yan, HAN Qian |
Department of Obstetrics and Gynecology, Qionglai Hospital of Traditional Chinese Medicine, Qionglai, Sichuan, 611530 China |
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Abstract 【Objective】To compare the effects of four schemes for treating cesarean scar pregnancy (CSP) and the time after treatment for human chorionic gonadotropin β (β-HCG) to drop to normal level in each scheme.【Methods】A total of 130 patients with CSP were enrolled in the study. The patients were randomly divided into group A (n=32), group B (n=30), group C (n=35) and group D (n=33) by random number table method, according to patient's own will. Patients in group A were treated with methotrexate alone, patients in group B were treated with methotrexate combined with uterus curettage, patients in group C were treated with uterine artery embolization combined with methotrexate and uterus curettage, and patients in group D were treated with hysteroscopic operation. The state of operation was compared among group B, group C and group D. The recovery indexes were compared among the four groups.【Results】The vaginal bleeding time, blood β-HCG dropping to normal time, and the time of lesion disappearing in group A were [ (29.55±5.20) d, (44.01±7.23) d, (50.21±6.34) d], respectively, which were significantly longer than those in group B, group C or group D (P<0.05). The intraoperative blood loss, length of hospitalization, vaginal bleeding time and time for blood β-HCG to drop to normal in group B were [ (152.74±58.59) ml, (12.33±3.72) d, (26.18±4.08) d, (31.14±6.14) d], respectively, which were significantly more or longer than those in group C or group D (P<0.05).【Conclusion】All four schemes are effective in the treatment of CSP. Uterine artery embolization combined with hysteroscopic surgery has advantages of a small amount of bleeding, complete debridement and quick recovery, however, it requires equipment and techniques. The most reasonable treatment plan should be chosen according to the actual condition of patients.
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Received: 13 April 2017
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