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Evaluation of AMH in Ovarian Function Before and After Laparoscopic Gynecological Surgery |
YANG Zhi-hong,CHEN Guang-yuan,XIE Jia-bin,et al |
Department of Gynecology, Songgang People's Hospital, Baoan District, Guangdong Province, Shenzhen 518105, Guangdong |
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Abstract 【Objective】To evaluate the value of anti-mullerian hormone (AMH) in the evaluation of ovarian function before and after laparoscopic gynecologic surgery.【Methods】From January 2016 to December 2016, 370 cases of gynecological diseases diagnosed and treated in gynecology and obstetrics department in our hospital were selected.There were 80 cases in ovary group, 90 cases in hysteromyoma group and 200 cases in fallopian tube group. The levels of AMH were compared at the time before operation, 6 weeks and 6 months after operation.【Results】The serum AMH levels in patients with ovarian chocolate cysts and those with non-chocolate cysts at 6 weeks and 6 months after operation were significantly lower than those before operation (P<0.05). The level of serum AMH 6 of months after operation was significantly lower than that of 6 weeks after the operation (P<0.05).However, the level of AMH in patients with ovarian chocolate cysts was significantly lower than that in patients with non-chocolate cysts (P<0.05). There was no significant difference in serum AMH between subtotal hysterectomy patients and hysteromyomectomy patients (P>0.05). 6 weeks and 6 months after operation, the serum AMH level in both groups was significantly lower than that before operation (P<0.05), and the level of serum AMH at 6 months after operation in both groups was significantly lower than that at 6 weeks after operation (P<0.05). The serum AMH level of subtotal hysterectomy patients was lower than that of hysteromyomectomy patients in the same period. There was no significant difference in serum AMH level between the unilateral salpingotomy group and the unilateral salpingotomy group + the contralateral salpingotomy group (P>0.05). The serum AMH level in unilateral salpingotomy group at months after operation was significantly lower than that of preoperation (P<0.05). There was no significant difference in serum AMH levels between the unilateral salpingotomy group and the unilateral salpingotomy group + the contralateral salpingotomy group (P>0.05).【Conclusion】Six months after operation, laparoscopic excision of ovarian cysts had adverse effects on ovarian reserve function, and the ovarian reserve of chocolate ovarian cysts decreased more obviously than that of non-chocolate ovarian cysts. Laparoscopic subtotal hysterectomy has a negative effect on ovarian reserve, while uterine myomectomy has little effect. The unilateral salpingotomy group and the unilateral salpingotomy group + the contralateral salpingotomy group under laparoscopy have adverse effects on ovarian reserve function.Appropriate surgical methods should be adopted according to the patient's condition and requirement.
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Received: 27 November 2017
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