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    					| Screening Method its Clinical Significance of Vaginal Intraepithelial Neoplasia (VAIN) after Hysterectomy for Cervical Lesions | 
  					 
  					  										
						| GUO Ya-bin, NIE Mei-fang, WU Xian-qing | 
					 
															
						| Department of Obstetrics & Gynecology, the Second Xiangya Hospital of Central South University, Changsha, Hunan.410011 | 
					 
										
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															    																	Received: 12 December 2016
																	    
															    															    															   	
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															 [1] Murta EF, Neves Junior MA, Sempionato LR,et al.Vaginal intraepithelial neoplasia: Clinical therapeutic analysis of 33 cases[J].Arch Gynecol Obstet,2005,272(4): 261-264.  [2] Gupta S, Sodhani P, Singh V, et al. Role of vault cytology in follow-up of hysterectomized women: results and inferences from a low resource setting[J].Diagn Cytopathol,2013,41(9):762-766.  [3] Schockaert S, Poppe W, Arbyn M,et al.Incidence of vaginal intraepithelial neoplasia after hysterectomy for cervical intraepithelial neoplasia: A restrospective study[J].Am J Obstet Gynecol,2008 , 199 (2) :1-5.  [4] Coughlan C, McAuliffe F, Bermingham N,et al.Vaginal cytology following primary hysterectomy for cervical cancer: Is it useful [J].Ir J Med Sci,2006,175(1):45-49.  [5] Woodman C, Jordan J, Wade-Evans T. The management of vaginal intraepithelial neoplasia after hysterectomy[J].BJOG, 1988 , 95 (10) :976-979.  [6] Cheung KW, Cheung VY. Hysterectomy for abnormal cervical smear when local excision is not possible[J].J Low Genit Tract Dis,2014,18(3):235-239.  [7] Frega A,Sopracordevole F, Assorgi C,et al.Vaginal intraepithelial neoplasia: a therapeutical dilemma[J] .Anticancer Res,2013,33(1):29-38.   [8] Van Nagell JR Jr, Rayburn W, Donaldson ES, et al. Therapeutic implications of patients of recurrence in cancer of the uterine cervix[J].Cancer,1979,44(6):2354-2361.  [9] Kalogirou D,Antoniou G,Karakitsos P,et al. Vaginal intraepithelial neoplasia (VAIN) following hysterectomy in patients treated for carcinoma in situ of the cervix[J].Eur J Gynaecol Oncol,1997,18(3):188-191.  [10] Elit L, Fyles AW, Devries-Aboud MC,et al.Gynecology cancer disease site group[J].Gynecol Oncol,2009,114(3):528-535. [11] Soisson AP, Geszler G, Soper JT,et al.A comparison of symptomatology, physical examination and vaginal cytology in the detection of recurrent cervical carcinoma after radical hysterectomy[J].Obstet Gynecol,1990,76(1):106-109. [12] De Vuyst H, Clifford GM, Nascimento MC,et al. Prevalence and type distribution of papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina,anus: A meta-analysis[J].Int J Cancer,2009,124(7): 1626-1636. [13] Li Z,Barron S,Hong W,et al.Surveillance for Recurrent Cancers and Vaginal Epithelial Lesions in Patients With Invasive Cervical Cancer After Hysterectomy.Are Vaginal Cytology and High-Risk Human Papillomavirus Testing Useful [J].Am J Clin Pathol,2013,140(5):708-714. [14] Boonlikit S, Noinual N.Vaginal intraepithelial neoplasia: A retrospective analysis of clinical features and colpohistology[J].J Obstet Gynaecol Res,2010,36(1): 94-100.      (本文编辑:詹道友) [收稿日期] 2016-12-12
 
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																					. [J]. JOURNAL OF CLINICAL RESEARCH, 2018, 35(1): 150-152. | 
																				 
																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																				 
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