经腹膜外改良逆行膀胱全切术+原位回肠新膀胱术治疗男性浸润性膀胱癌临床观察

doi:10.3969/j.issn.1671-7171.2017.09.014

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Abstract 【Objective】To investigate the clinical efficacy of extraperitoneal modified retrograde cystectomy combined with orthotopic ileal neobladder in the treatment of invasive bladder cancer in men.【Methods】In our hospital, 78 cases of invasive bladder cancer in male patients were randomly divided into observation group (39 cases) and control group (39 cases).They were treated with extraperitoneal modified retrograde cystectomy combined with orthotopic ileal neobladder and conventional cystectomy combined with orthotopic ileal neobladder. The blood loss, operation time, gastrointestinal function recovery time and postoperative hospital stay were compared between the two groups, and the urine control during the day and night 3 months and 6 months after operation in the two groups was also observed.The urine flow dynamics and complications were compared between the two groups at 6 months after operation.【Results】The intraoperative blood loss, operation time, gastrointestinal function recovery time and postoperative hospital stay in the observation group were significantly smaller than those in the control group (P＜0.05);day and night urinary continence had no significant difference in the two groups 3 months and 6 months after the operation (P＞0.05). However, the urinary continence during the daytime was better than that in the night, and the difference was statistically significant (P＜0.05).There was no significant difference in urodynamic parameters between the two groups at 6 months after operation (P＞0.05).The total incidence of complications in the observation group was 5.13%, significantly less than that in the control group 20.51% , and the difference was statistically significant (P＜0.05).【Conclusion】The treatment of male invasive bladder cancer with modified extraperitoneal cystectomy combined with orthotopic ileal neobladder is of remarkable clinical efficacy, which can effectively improve the patient's urine control with less complications. The therapy is safe and reliable and worthy of clinical application.

Key words： Peritoneum Cystectomy/MT Urinary Bladder Neoplasms/SU Ileum/SU Postoperative Complications

Received: 01 August 2017

PACS:

R737.14

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	WANG Zhi
	SHEN Kai
	LIAO You-gang

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WANG Zhi,SHEN Kai,LIAO You-gang. Clinical Analysis of Modified Radical Cystectomy Combined with Orthotopic Ileal Neobladder for Invasive Bladder Cancer in Male Patients[J]. JOURNAL OF CLINICAL RESEARCH, 2017, 34(9): 1711-1714.

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http://www.jcr.net.cn/EN/10.3969/j.issn.1671-7171.2017.09.014 OR http://www.jcr.net.cn/EN/Y2017/V34/I9/1711

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