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| Influence of Predeposited Combined with Salvaged Autotransfusion on Blood Clotting and Cellular Immune Function of Patients with Total Hip Arthroplasty |
| ZHENG Qiang, LI Shu-ping, MA Cui |
| Blood Transfusion Department, Beijing Tongren Hospital, Capital Medical University, BeiJing, 100176 |
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Abstract 【Objective】To study the influence of predeposited combined with salvaged autotransfusion on blood clotting and cellular immune function of patients with total hip arthroplasty.【Methods】From January 2013 to January 2016, 92 patients with total hip arthroplasty were selected from Beijing Tongren Hospital, Capital Medical University and General Hospital of PLA. Patients were divided into 2 groups randomly, : with 46 patients in the observation group (autotransfusion) and 46 patients in the control group (allogenic transfusion). The infection rate, blood routine (Hb, Hct and PLT), coagulation routine (FIB, PT, APTT and TT) and cellular immune function (CD3+, CD4+, CD8+, CD4+/CD8+ and NK) were compared between the two groups.【Results】The infection rate in the observation group was 2.17%(1/46), which was not significantly different from that in the control group 8.70%(4/46) (χ2=1.904, P>0.05). There were no significant differences in Hb, Hct, PLT, FIB, PT, and APTT at 2h and 24h after transfusion between the two groups(P>0.05). Compared to preoperative values, , the levels of CD3+, CD4+, CD4+/CD8+ and NK at 24h and 72h after transfusion in the control group decreased significantly (P<0.05). The levels of CD3+, CD4+, CD4+/CD8+ and NK in the observation group decreased significantly at 24h (P<0.05); however, there was no significant changes at 72h (P>0.05). There were significant differences in CD3+, CD4+, CD4+/CD8+and NK between the two groups after transfusion (P<0.05).【Conclusion】The safe and effective way of predeposited combined with salvaged autotransfusion has no impact on immune function. Thus it is superior to allogenic blood transfusion.
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Received: 04 February 2017
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2017, Vol. 34 
