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| Relationship between Adiponectin Dynamic Changes and Left Ventricular Systolic Function in Patients with Acute Myocardial Infarction before and after Percutaneous Coronary Intervention |
| ZHONG Wen |
| Third People's Hospital of Chengdu, Chengdu, Sichuan Province, 610000 China |
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Abstract 【Objective】To explore the relationship between the adiponectin (APN) dynamic changes and left ventricular systolic function in patients with acute myocardial infarction (AMI) before and after percutaneous coronary intervention (PCI). 【Methods】A total of 100 cases of AMI patients treated with elective PCI in our hospital from January 2015 to January 2016 were selected as the observation group, and 90 healthy examiners with the matching gender and age were selected as the control group. The levels of APN were detected in the both group before PCI as well as 1 month and 3 months after operation. The two-dimensional speckle tracking imaging was used to detect the left ventricular systolic function [left ventricular end diastolic volume (LVESV), left ventricular end systolic diameter (LVESD) and left ventricular ejection fraction (LVEF)] of the observation group. The correlation between APN and LVESV, LVESD, LVEF was analyzed. 【Results】The APN level before operation, 1 month and 3 months after operation were lower in the observation group than those in the control group (P＜0.05). The APN level of the observation group was higher at 1 month and 3 months after operation than it was before operation (P＜0.05), and the APN level at 3 months after operation was higher than that at 1 month before operation (P＜0.05). The levels of LVESV and LVESD at 1 month or 3 months after operation in the observation group were lower than those before operation, while the LVEF level was higher than that before operation (P＜0.05).The levels of LVESV and LVESD at 3 months after operation were lower than those at 1 month after operation, while the LVEF level was higher than that at 1 month after operation (P＜0.05). Pearson correlation analysis showed that serum APN was negatively correlated with the LVESV and LVESD (r=-0.716, -0.618,P＜0.05), and positively correlated with LVEF (r=0.689,P＜0.05). 【Conclusion】APN level of AMI patients after PCI is closely related with left ventricular systolic function.
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Received: 25 April 2017
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[1]潘文,刘峰,刘庆军,等.主动脉内球囊反搏对高危急性心肌梗死直接经皮冠状动脉介入治疗患者近期生存率的影响[J].医学临床研究,2013,30(12):2478-2479,2480.
[2] 吴向军,王庆元,刘海涛,等.瑞舒伐他汀强化治疗对心肌梗死患者经皮冠状动脉介入术后脂联素和脑钠肽及左心室重构的影响[J].中国医药,2014,9(1):9-13.
[3] 郭立新,梁文华.ACS患者血清血尿酸、同型半胱氨酸及脂联素水平与冠状动脉病变的关系[J].湖南师范大学学报(医学版),2013,10(2):17-19.
[4] 李杨,秦勤,任蓓等.原发性高血压患者血清脂联素及其基因多态性与冠心病的相关性研究[J].天津医药,2014,42(9):903-907,908.
[5] 李强,郭壮波,黎庆梅等.芪苈强心胶囊对冠心病合并心力衰竭患者血清脂联素水平及心功能的影响[J].中国病理生理杂志,2014,30(6):1119-1122.
[6] White HD, Thygesen K, Alpert JS,et al. Joint ESC/ACCF/AHA/WHF Task Force for the Universal Definition of Myocardial Infarction. Third universal definition of myocardial infarction[J].Circulation,2012, 126(16):2020-2035.
[7] 李玉群,梁贤球,何晟,等.稳定期COPD患者营养状况与血清脂联素、肺功能、CAT评分的关系[J].安徽医科大学学报,2014,49(7):969-972.
[8] 王立坤,武雪亮,杨占清,等.2型糖尿病患者血清抵抗素、瘦素、脂联素水平与外周动脉弹性及舒张功能的相关性研究[J].重庆医学,2016,45(35):4956-4958,4962.
[9] 苏牟潇,陈忠伦,姚力瑛,等.瘦素、脂联素对进展性脑梗死的预测价值及预后的影响[J].中国医师杂志,2014,16(7):988-990.
[10] 王薇, 李丹, 黄雪兰,等. 实时三维超声心动图对急性心肌梗死经皮冠状动脉介入治疗前后左心室功能变化的评价[J].中国全科医学, 2015,18(27):3371-3375.
[11] 陈玉媛, 谢明星, 王静,等.二维斑点追踪成像技术评价舒张性心力衰竭患者左心室局部收缩功能[J].中国医学影像学杂志,2012,20(8):614-617.
[12] 祁明, 李玉宏.斑点追踪显像技术评价PCI对急性心肌梗死患者左心室局部收缩功能的影响[J].中国医学影像技术,2011,27(2):308-312. |
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2017, Vol. 34 
