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Correlation between Dyslipidemia and Stroke in Patients undergoing Maintenance Hemodialysis |
HE Jing-dong |
Department of Nephrology, the Second Affiliated Hospital of Chengdu Medical College (416 Hospital of Nuclear Industry), Chengdu 610051, Sichuan, China |
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Abstract 【Objective】To study the correlation between dyslipidemia and stroke in patients undergoing maintenance hemodialysis (MHD).【Methods】Atotal of 120 patients undergoing MHD (observation group) and 60 cases of healthy persons (control group) were enrolled in the study. According to the occurrence of stroke, the patients were divided into stroke group and non-stroke group. The blood lipids were compared among groups.【Results】Levels of triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) showed significant differences between the observation group and the control group (P<0.05). Levels of TG and LDL-C in stroke group were (2.76±0.94) mmol/L and (3.41±0.72) mmol/L, respectively while those in the non-stroke group were (1.68±0.79) mmol/L and (2.75±0.73) mmol/L, respectively (P<0.05). Multivariate Logistic regression analysis showed that the independent risk factors for stroke in patients undergoing MHD included age, dialysis time, systolic blood pressure before dialysis, TG and LDL-C levels. 【Conclusion】Dyslipidemia easily occur in patients undergoing MHD. Advanced age, long dialysis time, systolic blood pressure before dialysis, TG and LDL-C levels are the risk factors for the occurrence of stroke.
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Received: 05 March 2017
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