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| Value of UE Combined with Microcalcification Enhanced Technique in the Differential Diagnosis of Benign and Malignant Breast Nodules |
| WANG Xiao-qing, HE Jing-jun, HUANG Hong-yan |
| Dept. of Physical Examination,the Second People's Hospital of Guangdong, Guangzhou ,Guangdong,510317, China |
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Abstract 【Objective】To analyze the clinical value of ultrasound elastography (UE) combined with microcalcification enhanced technique in differential diagnosis of benign and malignant breast nodules. 【Methods】The clinical data of 80 cases of patients with breast masses (95 nodules) who were examined with ultrasound in the hospital during March 2013 ~ February 2016 were retrospectively analyzed. All patients completed the two-dimensional ultrasound, UE and ultrasound firefly microcalcification enhancement scanning. Pathological findings were used as controls, and the clinical value of UE combined with microcalcification enhanced technique in differential diagnosis of benign and malignant breast nodules was analyzed. 【Results】The sensitivity, specificity and accuracy of two dimensional ultrasound in differential diagnosis of benign and malignant breast nodules were 85.19% (46/54), 65.85% (27/41) and 76.84% (73/95), respectively, while those of ultrasound firefly microcalcification enhanced technique were 85.71% (54/68), 77.78% (21/27) and 78.95% (75/95), respectively, those of UE Itoh 5 method were 88.14% (52/59), 77.78% (28/36) and 84.21% (80/95), respectively, and those of UE+firefly microcalcification enhanced technique were 95.08% (58/61), 94.12% (32/34) and 94.74% (90/95), respectively. The diagnostic specificity of UE+firefly microcalcification enhanced technique was higher than that of two dimensional ultrasound, firefly technique or UE Itoh 5 method (χ2=5.141, 4.026, 4.026, P＜0.05), and its accuracy was higher than that of two dimensional ultrasound or firefly technique (χ2=4.014, 3.966,P＜0.05). 【Conclusion】The combination of UE and firefly micro calcification enhancement technique has higher clinical value in identifying benign and malignant breast nodules, and has higher sensitivity, specificity and accuracy. It can be used as an effective means for screening breast diseases.
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Received: 22 March 2017
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2017, Vol. 34 
