妊娠中晚期产妇血清25羟维生素D3与妊娠结局的相关性分析

doi:10.3969/j.issn.1671-7171.2017.07.013

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Abstract 【Objective】To investigate the relationship between serum 25-hydroxyvitamin D3in pregnant women in the second or third-trimester of pregnancy and pregnancy outcomes. 【Methods】The clinical data of 124 pregnant women in the second or third-trimester of pregnancy who received antenatal care in our hospital between February 2014 and January 2015 were analyzed retrospectively. According to the levels of serum 25 (OH)D3, the pregnant women were divided into the deficiency group [25 (OH) D3 level＜25 nmol/L,n=42], insufficiency group (25 nmol/L＜ 25 (OH) D3 level ＜ 50 nmol/L,n=52) and sufficiency group (25 (OH) D3 level ＞75 nmol/L,n=30). The adverse pregnancy outcomes and complications were compared between groups. 【Results】The incidence rates of abortion, preterm labor, preeclampsia, bacterial vaginosis and anemia in the deficiency group (35.71%, 47.62%, 30.92%, 38.1%, 28.57%) were significantly higher than those in the insufficiency group (15.38%, 26.92%, 19.23%, 6.67%, 17.31%) and the sufficiency group (6.67%,16.67%, 3.33%, 13.33%, 25.0%)(P＜0.05). The delivery cycle of the deficiency group [(37.12±0.52) weeks] was significantly shorter than that of the insufficiency group [(38.24±1.02) weeks] and the sufficiency group [(39.57±1.45) weeks](P＜0.05). 【Conclusion】Deficiency or insufficiency of serum 25-hydroxyvitamin D3 in pregnant women in the second or third trimester of pregnancy can increase the risk of adverse pregnancy outcomes and the incidence of pregnancy complications, and it can lead to fetal growth retardation.

Key words： Pregnancy Trimester, Second Pregnancy Trimester, Third Calcifediol/BL Pregnancy Outcome

Received: 15 November 2016

PACS:

R714.1

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	Articles by authors
	GAO Jing-jing
	ZHOU Xiao-ping
	ZHAI Jin-ya
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Cite this article:

GAO Jing-jing,ZHOU Xiao-ping,ZHAI Jin-ya, et al. Study on the Relationship Between Serum 25-hydroxyvitamin D in Pregnant Women in the Second or Third-trimester of Pregnancy and Pregnancy Outcomes[J]. JOURNAL OF CLINICAL RESEARCH, 2017, 34(7): 1288-1290.

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http://www.jcr.net.cn/EN/10.3969/j.issn.1671-7171.2017.07.013 OR http://www.jcr.net.cn/EN/Y2017/V34/I7/1288

[1] 钟田花,刘紫菱,王海燕,等.不同孕期孕妇血清25-羟维生素D水平的研究[J].国际医药卫生导报,2015,21(19):2828-2830.
[2] 袁北芳, 任立红. 维生素D及其受体的免疫调节作用研究进展[J].国际免疫学杂志, 2014, 37(1):52-56.
[3] 李冬梅.孕妇维生素D缺乏及其对胎儿的影响[J].医药前沿,2015,5(12):362-363.
[4] 周辉,谭译,肖思科,等.孕早期血清25羟维生素D水平与妊娠期糖尿病的相关性[J].医学临床研究,2015, 32(10):2043-2044.
[5] 黄艳红,李红丽.复方丹参对早发型重度子痫前期患者妊娠结局及新生儿的影响[J].解放军医药杂志,2016,28(7):96-99.
[6] 李媛,吴晓萍,张蕾,等.妊娠期维生素D缺乏对孕妇及新生儿影响的研究进展[J].实用妇科内分泌电子杂志,2016,3(5):12-13.
[7] Ness RA, Miller DD, Li W. The role of vitamin D in cancer prevention [J].Chin J Nat Med,2015, 13(7):481-497.
[8] 蔡芬.血清维生素D、甲状旁腺激素水平与妊娠期糖尿病的相关性研究[J].国际检验医学杂志,2016,37(15):2152-2153.
[9] 向菲, 蒋佳, 欧亚萍,等. 贵阳市妊娠中晚期妇女维生素D现状研究[J].中华内分泌代谢杂志, 2014, 30(6):486-489.
[10] 李恒芝, 贺志雄, 颜琼娴,等. 妊娠期母体营养调控子代骨骼发育与代谢的研究进展[J].基因组学与应用生物学, 2015,34(8):1663-1668.
[11] 庄学玲, 竺智伟, 朱东波,等. 孕母和新生儿维生素D水平及其相关因素的分析[J].中华儿科杂志, 2012, 50(7):498-503.
[12] 吴国才,梁园园,李慧,等.中国胶东地区中晚期孕妇血清维生素D水平检测分析[J].实用医学杂志,2016,32(9):1547-1548.
[13] 江巍, 高凤荣. 维生素D缺乏相关性疾病研究进展[J].中国骨质疏松杂志, 2014,20(3):331-337.
[14] 陈香,孙静,庞颖,等.妊娠期糖尿病危险因素及母婴结局的临床研究[J].湖南师范大学学报(医学版),2015,60(4):101-103.
[15] 王丽萍, 黄金. 孕期维生素D 水平与不良妊娠结局相关性研究进展[J].实用医学杂志, 2015,31(20):3446-3448.