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| Comparison of Prognosis of Patients with Liver Metastases of Colorectal Cancer Treated by Microwave Ablation, Transhepatic Arterial Chemotherapy and Embolization and Systemic Chemotherapy |
| AI Dong-mei, QIAO Xiu-zhen, YU Hong-wei,et al |
| Department of Oncology ,The Second People's Hospital of Hengshui(In cancer hospital 053000 |
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Abstract 【Objective】To compare the prognosis of patients with liver metastases of colorectal cancer treated by microwave ablation, transhepatic arterial chemotherapy and embolization (TACE) and systemic chemotherapy. 【Methods】According to different treatment methods, 80 cases of patients with liver metastases of colorectal cancer were divided into the observation group (treated by microwave ablation+TACE sequential therapy) and the control group (treated by systemic chemotherapy). The short-term curative effect and prognosis (survival) were compared between the two groups, and the changes of cell immune function before and after treatment were determined and recorded. 【Results】The short-term objective response rate (ORR) of the observation group was 66.67% (28/42)while that of the control group was 42.10%(16/38), and the difference was significant (P＜0.05). After initial treatment, positive rate of CD3+, CD4+ and the ratio CD4+/CD8+ were significantly higher, and CD8+ was significantly lower in the observation group than those in the same group before treatment and those in the control group after treatment (P＜0.05). The median survival time of the observation group was 26.00 months while that of the control group was 13.60 months (P＜0.05). 【Conclusion】On the basis of systemic chemotherapy , microwave ablation + TACE can significantly improve the effective rate of treatment for patients with liver metastases of colorectal cancer, significantly improve the immune function and prolong the survival time of patients.
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Received: 01 April 2017
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2017, Vol. 34 
