高血压患者左心室肥厚及其功能改变的影响因素分析

doi:10.3969/j.issn.1671-7171.2017.06.016

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Abstract 【Objective】To investigate the influencing factors of left ventricular hypertrophy and functional changes in patients with hypertension.【Methods】One hundred cases of patients with hypertension were selected from January 2014 to April 2016 in our hospital were selected as the research subject, according to the ambulatory arterial stiffness index (AASI) were randomly divided into observation group (AASI>0.51,n=45) and control group (AASI=0.51,n=55). Non-invasive cuff blood pressure instrument was used for automatic monitoring of patients in two groups of 24 h ambulatory blood pressure; left ventricular end diastolic diameter (LVDd), interventricular septal thickness (IVST), left ventricular posterior wall end diastolic thickness (LVDd), relative wall thickness (LVPWTD), ambulatory arterial stiffness index (AASI), left ventricular mass index (LVMI) of the two groups were measured by SIEMENS S2000 color ultrasonic diagnostic instrument; 24h mean systolic pressure (24hSBP), 24h mean diastolic pressure (24hDBP) and 24h dynamic pulse pressure (24hPP) were compared between the two groups; fasting blood glucose (FPG), three acyl glycerol (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and other biochemical indexes were compared between the two groups.【Results】24hSBP and 24hPP of the observation group were significantly higher than those of the control group, 24hDBP and 24hHR were significantly lower than those of the control group, the difference was statistically significant (both P<0.05). The difference of serum TG, TC, HDL-C levels, age, course of disease, AASI and LVMI between the observation group and the control group was statistically significant (P<0.05). The index for the two groups of patients had statistical differences in the logistics regression analysis, 24hSBP, 24hPP and AASI were independent risk factors led to the change of hypertension patients with left ventricular hypertrophy and function (P<0.05).【Conclusion】24hSBP, 24hPP and AASI are independent risk factors for left ventricular hypertrophy and functional changes in hypertensive patients. Active treatment is needed to control their blood pressure level and to improve their awareness of hypertension.

Key words： Hypertension Hypertrophy, Left Ventricular Arteriosclerosis Risk Factors

Received: 27 December 2016

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R544.1

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	WANG Qi
	LIN Zhen
	CUI Xiao-hong

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WANG Qi,LIN Zhen,CUI Xiao-hong. Analysis of I0nfluencing Factors of Left Ventricular Hypertrophy and Functional Changes in Patients with Hypertension[J]. JOURNAL OF CLINICAL RESEARCH, 2017, 34(6): 1093-1096,1098.

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http://www.jcr.net.cn/EN/10.3969/j.issn.1671-7171.2017.06.016 OR http://www.jcr.net.cn/EN/Y2017/V34/I6/1093

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(本文编辑:张兴珍) [收稿日期] 2016-12-27