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| A Comparative Study on the Effects of Three Surgical Methods for Treating Middle and Lower Esophageal Cancer and the Changes of Stress Indexes |
| LI Cheng-lin |
| The Affiliated First HuaiAn Hospital of NanJing Medical University,Huaian Jiangsu 223300 |
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Abstract 【Objective】 To observe the effects of three surgical methods for treating middle and lower esophageal cancer and the changes of stress indexes. 【Methods】Eighty patients with middle and lower esophageal cancer were divided into three groups. 25 cases in group A were treated by left thoracic single-port resection, while 28 cases in group B were treated by right thoracic and abdominal resection, and 27 cases in group C were treated by left neck, right thoracic and median abdominal resection. The perioperative indexes and the number of dissected lymph nodes were compared between the groups, the white blood cell count (WBC), serum free triiodothyronine (FT3), free thyroxine (FT4), CRP, cortisol, postoperative complications and 1-year recurrence rate were also compared. 【Results】The operation time, postoperative hospitalization time, intraoperative bleeding volume, drainage time and the number of dissected lymph nodes of the Group B and the Group C were significantly higher than those in the Group A, and the Group C was significantly higher than the B group, the difference was significant (P<0.05). CRP and cortisol of the Group C were significantly higher than those in the Group A and the Group B (P<0.05), but there was no significant difference in WBC, FT3, FT4 and postoperative complications between the three groups(P>0.05). One year recurrence rate the Group A was significantly higher than that of the Group B and the Group C (P<0.05).【Conclusion】 The three surgical methods have their own characteristics, and the appropriate surgery should be chosen according to the conditions of patients.
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Received: 12 December 2016
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[1] 任清泉, 杨扬, 张孟斌,等. 食管癌根治术后患者预后的相关研究[J].湖南师范大学学报医学版, 2015,12(4):34-37.
[2] 张康, 张广敬, 崔宏伟,等. 胸中段食管癌经颈胸腹三野淋巴结清扫与经左胸单切口二野淋巴结清扫的效果比较[J].山东医药, 2014,54(28):52-54.
[3] 吴晓峰, 肖远光, 毛志福. 食管癌切除术后胸胃瘘发生的原因和治疗[J].临床误诊误治, 2012, 25(2):64-65.
[4] 周柏涛, 艾义国, 李雪莲,等. 经上腹、右胸联合切口手术治疗中段食管癌的疗效观察[J].医学临床研究, 2011, 28(6):1090-1091.
[5] 史冬森. 右胸前外侧及上腹两切口在食管中段癌手术中的应用[J].安徽医药, 2011, 15(7):873-874.
[6] 张孝国, 易德茂, 唐小军. 经颈胸腹三切口手术治疗胸中上段食管癌76例疗效观察[J].西部医学, 2012, 24(7):1274-1276.
[7] 马明全, 姜宏景, 弓磊,等. 胸腔镜与开放食管癌根治术后并发症及应激反应的比较研究[J].中华胃肠外科杂志, 2016, 19(4):401-405.
[8] 陈新, 刘洋伯, 陈和平,等. 腹腔镜胆囊切除术患者围手术期机体应激情况及肝功能变化研究[J].海南医学院学报, 2012, 18(7):910-912.
(本文编辑:王沪湘) [收稿日期] 2016-12-12
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2017, Vol. 34 
