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| Effect of Laparoscopic Ovarian Cyst Removal on Ovarian Reserve Function in Female Patients |
| FU Jie, CHEN Hui-juan, LUAN Ying, et al |
| Department of Obstetrics and Gynecology, Central Hospital of Jiamusi, Jiamusi, Heilongjiang 154002, China |
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Abstract Objective To investigate the effect of laparoscopic ovarian cystectomy on ovarian reserve function in women with endometriosis. Methods Eighty-four patients with endometriosis cysts who were admitted to the obstetrics and gynecology department in our hospital between from April 2013 and to March 2015 were selected as the study subjects and were randomized into the observation group (n=42) and the control group (n=42) according to the order of admission. The control group was treated with laparoscopic open reduction of cyst, and the observation group was treated with laparoscopic ovarian cyst removal. All patients were treated with gonadotropin releasing hormone (GnRH-a) after operation. The changes of ovarian function indexes such as serum follicle stimulating hormone (FSH), luteinizing hormone (LH) and estrogen (E2) levels, basic number of follicles and ovarian volume in the two groups were recorded before operation and at 6 months after operation. The status of fertility, including the rate of successful re-pregnancy and recurrence rate in 1 year after operation and menstruation were compared between the two groups. Results At six months after operation, levels of LH and E2 were significantly lower than those before operation, and the levels LH and E2 in observation group were significantly lower than those in control group (P<0.05). There were no significant changes of FSH at 6 months after operation (P>0.05); The basic number of follicles and aveareg ovarian volume were significantly lower than those before operation (P<0.05). There was no significant difference in menstrual period and menstrual cycle between the two groups before operation and at 1 year after operation (P>0.05). The pregnancy rate of observation group in 1 year after operation was significantly higher than that of control group while the recurrence rate was significantly lower than that in the control group (P<0.05). Conclusion The ovarian reserve function is affected in a short time after laparoscopic ovarian cystectomy, Compared with traditional laparotomy, laparoscopic ovarian cystectomy still has obvious advantages in terms of pregnancy rate, postoperative recovery and recurrence rate.
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Received: 03 November 2016
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. [J]. JOURNAL OF CLINICAL RESEARCH, 2017, 34(5): 928-931. |
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2017, Vol. 34 
