慢性化脓性中耳炎病原学特点及术后不干耳影响因素分析

doi:10.3969/j.issn.1671-7171.2017.03.023

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (0 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract 【Objective】To analyze the pathogen characteristics of chronic suppurative otitis media and postoperative factors affecting of occurance of non-dry ear in order to improve the cure rate of chronic suppurative otitis media and provide a basis to reduce the complications.【Methods】A total of 243 patients who were treated with surgery for chronic suppurative otitis media in our hospital from Jan 2013 to Jan 2015 were included in this study. Etiology monitoring was conducted on the middle ear cavity discharge , and analysis was carried out on pathogenic bacterial distribution and drug sensitivity;The patients were divided into dry ear group and non-dry ear group; statistical analysis was made on age, gender, smoking, alcohol abuse, basic disease, nutritional status, clinical data and laboratory results; the postoperative risk factors of non-dry ear were evaluated.【Results】 Pathogenic bacteria was detected in 213 of 255 ear pus samples, the detection rate was 83.5%; A total of 268 strains of pathogens were detected , including 154 Gram- positive bacteria which accounted for 57.5% of total pathogens, and 92 Gram- negative ones which accounted for 34.3%; and 22 fungi ones accounting for 8.2%. Drug sensitive tests showed that Gram- positive bacteria was sensitive to glycopeptide antibiotics , and the Gram-negetive was sensitive to polymyxin B and carbapenems; Fungi was sensitive to antifungal drug. Non-dry ear after surgery was associated with smoking, diabetes and fungal infections (especially mucormycosis related), the difference of the two groups was statistically significant (P<0.05).【Conclusion】The treatment of chronic suppurative otitis media should be based on sensitive antibiotic. Attention should be paid to the possibility of fungal infection, and patients are strongly advised to stop smoking and strictly control blood sugar.

Key words： Otitis Media, Suppurative Chronic Disease Microbial Sensitivity Tests Bacteria Postoperative Complications Risk Factors

Received: 23 November 2016

PACS:

R764.21

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	WANG Fang
	HU Xiao-yan
	JIANG Liang

Cite this article:

WANG Fang,HU Xiao-yan,JIANG Liang. Pathogenic Analysis of Chronic Suppurative Otitis Media and the Influencing Factors of Non-dry Ear after Surgery[J]. JOURNAL OF CLINICAL RESEARCH, 2017, 34(3): 486-489.

URL:

http://www.jcr.net.cn/EN/10.3969/j.issn.1671-7171.2017.03.023 OR http://www.jcr.net.cn/EN/Y2017/V34/I3/486

[1] Li MG, Hotez PJ, Vrabec JT, et al. Is chronic suppurative otitis media a neglected tropical disease [J].PLoS Negl Trop Dis,2015,9(3):e0003485.
[2] 何益梅.慢性化脓性中耳炎手术中患者听力受损的高危因素及防治对策[J].国际检验医学杂志, 2015,36 (10):1362-1363.
[3] Mironov AA. Chronic purulent otitis media[J].Vestn Otorinolaringol,2011,(5):72-76.
[4] 陈美珍,曾薇,林志敏,等.慢性化脓性中耳炎患者手术前后生活质量调查及其影响因素分析[J].医学临床研究,2016,33(7):1359-1361.
[5] Emir H, Ceylan K, Kizilkaya Z, et al. Success is a matter of experience: type 1 tympanoplasty : influencing factors on type 1 tympanoplasty[J]. Eur Arch Otorhinolaryngol,2007,264(6):595-599.
[6] 田勇泉.耳鼻咽喉头颈外科学[M].北京:人民卫生出版社,2013:330.
[7] 孙建军, 刘阳. 中耳炎临床分类和手术分型指南(2012)解读[J]. 中华耳鼻咽喉头颈外科杂志,2013,48(1):6-10.
[8] Saunders J, Murray M,Alleman A. Biofilms in chronic suppurative otitis media and cholesteatoma: scanning electron microscopy findings[J].Am J Otolaryngol,2011,32(1):32-37.
[9] 赵远新, 施思斯, 刘振. 173例慢性化脓性中耳炎的细菌学及药物敏感性分析[J]. 现代医药卫生,2007,23(3):423-425.
[10] 顾兴智, 尤乐都斯?克尤木, 程秀琴, 等. 新疆慢性中耳炎细菌学分析及动态变化研究[J].中国耳鼻咽喉颅底外科杂志,2014,20(3):223-227.
[11] 刘佳丽, 王维, 王子萌, 等. 555例慢性化脓性中耳炎的病原学及药物敏感性分析[J]. 第三军医大学学报,2016,38(21):2349-2352.
[12] 樊军, 高金锁, 徐广森,等. 162例慢性化脓性中耳炎病原菌及耐药性分析[J].中国医院药学杂志, 2011, 31(16):1382-1383.
[13] 刘春玲, 陈妙儿, 张少燕,等.耳部炎性疾病的细菌学及药物敏感性分析[J].中国医药导报, 2012,9(16):111-112.
[14] 刘娜, 思超, 高英,等.影响中耳炎术后不干耳的相关因素研究[J]. 延安大学学报:医学科学版,2016,14(1):20-22.
[15] 方敏.慢性化脓性中耳炎不同术式治疗的临床分析和疗效评价[D].四川医科大学,2015.
[16] Mushi MF, Mwalutende AE, Gilyoma JM, et al. Predictors of disease complications and treatment outcome among patients with chronic suppurative otitis media attending a tertiary hospital, Mwanza Tanzania[J]. BMC Ear Nose Throat Disord,2016,16:1.
[17] Chung JH, Lee SH, Woo SY, et al. Prevalence and associated factors of chronic suppurative otitis media: Data from the Korea National Health and Nutrition Examination Survey, 2009-2012[J]. Laryngoscope,2016,126(10):2351-2357.
[18] 付健, 孔祥云, 樊军. 慢性化脓性中耳炎患者真菌感染的临床分析[J].中华医院感染学杂志,2014,20(8):2008-2010.