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| Effect of Autonomic nervous Function on Retinal Vascular Diameter and Carotid Intima-media Thickness (CIMT) in Patients with Hypertension |
| LV Shao-kun |
| Qujing First People's Hospital, Yunnan 655000, China |
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Abstract 【Objective】To investigate the effect of autonomic nervous function on retinal vascular diameter and carotid intima-media thickness (CIMT) in patients with hypertension.【Methods】One hundred and twenty-eight patients with hypertension admitted to our hospital from September 2015 to September 2016 were selected as the subjects; 24h dynamic electrocardiogram was monitored by heart rate variability (HRV); those with the normal R-R interval standard deviation (SDNN) >100 ms were divided to normal group (n=54), and those with SDNN <100 ms were divided to abnormal group(n=74); the blood pressure, retinal vessel diameter and CIMT were compared between the two groups.【Results】 Low frequency (LF), high frequency (HF), SDNN heart rate variability (HRV) index of the abnormal group were significantly lower than the normal group,the blood pressure variability (BPV) was significantly higher than that of the normal group, the difference was statistically significant (P<0.05); the central retinal artery diameter (CRAE), the central retinal vein diameter (CRVE) and the fractal dimension (Df) of the abnormal group were significantly lower than those of the normal group, the difference was statistically significant (P<0.05); the abnormal group CIMT level was significantly higher than that of the normal group, the difference was statistically significant (P<0.05). By logistic regression analysis, SDNN was an independent risk factor for BPV, CRAE, Df and CIMT
(P<0.05).【Conclusion】 Autonomic nervous function has significant effects on HRV, retinal vessel diameter and CIMT vascular lesion in patients with hypertension.
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Received: 05 December 2016
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2017, Vol. 34 
