妊娠期维生素D水平与母婴结局的相关性

doi:10.3969/j.issn.1671-7171.2017.02.030

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Abstract 【Objective】 To investigate the relationship between vitamin D (VD) intake during pregnancy and maternal and neonatal outcomes.【Methods】One hundred pregnant women in middle-late pregnancy, who received antenatal care in our hospital between January 2015 and January 2016, were selected as the observation group while 60 non-pregnant healthy women were selected as the control group at the same time period. The levels of 25 hydroxyvitamin D₃ [25(OH)D₃] were determined by enzyme linked immunosorbent assay. According to the levels of 25(OH)D3, women in the observation group were divided into the deficient group, the insufficient group and the normal sub groups. The maternal and neonatal outcomes were compared among these groups. 【Results】 The average level of serum 25(OH)D₃ in the observation group was [(42.58±11.34) nmol/L], which was significantly lower than that in the control group [(53.36±10.82) nmol/L](P<0.05). The VD normal group, deficient group and insufficient group showed incidence rates of fetal distress to be 3.85%, 11.67% and 35.71% respectively, abortion to be 3.85%, 10% and 35.71% respectively, bacterial vaginosis to be 0.00%, 10.00% and 28.57% and gestational age to be (39.50±1.42), (38.10±2.00) and (37.28±0.50) respectively. Those differences were statistically significant (P<0.05). There were no significant differences in gestational diabetes, gestational hypertension, cesarean section, anemia, neonatal birth weight, height and head circumference among these groups (P>0.05). 【Conclusion】 VD insufficiency or deficiency during pregnancy will increase the risk of fetal distress, abortion and bacterial vaginosis as well as significantly shorten the gestational age. The level of VD during pregnancy has nothing to do with the growth of newborns.

Key words： Pregnant Women Vitamin D Pregnancy Outcome Calcifediol

Received: 15 November 2016

PACS:

R714.14

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	ZHANG Wei
	WEI Jian-tao
	CHEN Xiao-lan

Cite this article:

ZHANG Wei,WEI Jian-tao,CHEN Xiao-lan. Study on the Relationship between Vitamin D Intake during Pregnancy and Maternal and Neonatal Outcomes[J]. JOURNAL OF CLINICAL RESEARCH, 2017, 34(2): 300-302.

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http://www.jcr.net.cn/EN/10.3969/j.issn.1671-7171.2017.02.030 OR http://www.jcr.net.cn/EN/Y2017/V34/I2/300

[1]	. [J]. JOURNAL OF CLINICAL RESEARCH, 2017, 34(2): 386-388.