|
|
|
| Effect of Different Anesthesia Methods on Physiological and Biochemical Changes in Patients Undergoing BAL under Mechanical Ventilation |
| ZHAO Jing-xia |
| ICU,The Third People's Hospital of Xingtai,Hebei 054000 |
|
|
|
Abstract 【Objective】 To observe the effects of different anesthesia methods on physiological and biochemical changes in patients undergoing bronchoalveolar lavage (BAL) under mechanical ventilation . 【Methods】A total of 80 cases who underwent BAL under mechanical ventilation in ICU were selected as study subjects and were randomly divided into two groups, 40 cases in each group. The control group were treated with lidocaine surface anesthesia, while the observation group were treated with lidocaine surface anesthesia combined with fentanyl anesthesia. The changes of heart rate, blood pressure, body temperature, blood gas parameters and biochemical indicators were compared between the two groups after operation. 【Results】 There were no significant differences between the two groups at the beginning of anesthesia, after 10min, 20min and 30min of anesthesia and at the end of anesthesia (P>0.05). The blood gas indexes showed no significant difference between the two groups before operation (P>0.05). After operation, the PH , PaCO2, PaO2 and SaO2 in the control group were significantly decreased (P<0.05), and the blood gas indexes in the observation group were higher than those in the control group after operation (P<0.05). The blood biochemical indexes showed no significant differences between the two groups before operation (P>0.05). After operation, Hb, PLT,HCT, ALT and AST in the two groups were decreased, and the above indexes in the observation group were higher than those in the control group (P<0.05). 【Conclusion】Compared with the lidocaine surface anesthesia alone, lidocaine plus fentanyl can better maintain the vital signs, the blood gas indexes and biochemical indexes in the patients undergoing BAL under mechanical ventilation.
|
|
Received: 15 June 2016
|
|
|
|
|
|
[1] 朱晨, 赵亚滨, 孔灵菲, 等. 涎液化糖链蛋白6在特发性肺纤维化患者支气管肺泡灌洗液和血清中的表达及临床意义[J].中国呼吸与危重监护杂志, 2015, 14(3): 225-228.
[2] Vanderhelst E,Hanon S,Verbanck S,et al.Whole-lung lavage: A successful treatment for restoring acinar ventilation distribution in primary acquired pulmonary alveolar proteinosis[J].Res Int Rev Thorac Dis,2012,84(1):70-74.
[3] 赵彤,耳建旭,韩建阁,等.静脉全麻置入喉罩吸氧下行支气管镜肺泡灌洗治疗观察[J].天津医药,2012,40(9):944-945.
[4] 高瑞君,胡振宇,沈有舟,等.尘肺患者支气管镜肺泡灌洗中静脉麻醉的应用[J].中华劳动卫生职业病杂志,2014,32(9):699-700.
[5] 毕虹,陈敏,金志贤,等.经支气管镜肺泡灌洗治疗尘肺病的价值分析[J].昆明医科大学学报,2014,35(6):152-153.
[6] 范江花, 张新萍, 胥志跃, 等. 纤维支气管镜检查和肺泡灌洗术在重症肺部感染中应用意义[J].中国小儿急救医学, 2015, 22(007): 449-453.
[7] Bonella F,Bauer PC,Griese M,et al.Wash-out kinetics and efficacy of a modified lavage technique for alveolar proteinosis[J].Eur Res J,2012,40(6):1468-1474.
[8] 张劬,尤秀芝.全肺大容量灌洗治疗肺泡蛋白沉积症麻醉体会[J].医学理论与实践,2012,25(23):2931-2932.
[9] 刘渊泉.不同麻醉方式对ICU机械通气下支气管肺泡灌洗患者的疗效影响[J].临床肺科杂志,2014,19(3):572-573. |
|
|
|
2017, Vol. 34 
